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RMJ. 2022; 47(2): 271-274


Role of adenosine receptors in cardiovascular disorders and novel corona virus infection

Muhammmad Atif, Abdullah Alsrhani, Farrah Naz, Iahtisham-Ul- Haq, Muhammad Imran, Sidra Khalid.

Abstract
Objective: To assess the importance of adenosine signaling in cardiovascular disorders (thrombosis, ischemia) and novel corona virus infection.
Methodology: A specified web search was done to gather the relevant information using different scientific research forums and databases like WHO database, Pubmed and Google Scholar etc.
Results: Adenosine receptors are P1 type of purinergic receptors and belong to G protein-coupled receptors (GPCRs), which is the largest family of integral membrane bound proteins receptors. Adenosine receptors are further classified into four subclasses known as A1, A2A, A2B, and A3. All four subclasses are being mediated by extracellular adenosine and perform a key role in a wide range of physiological functions such as immune system modulation, angiogenesis and sleep regulation. Adenosine receptors are thought to play a significant role in many pathophysiological conditions including cardiovascular disorders such as ischemia and thrombosis and novel corona virus infection making it a key target against these disorders.
Conclusion: We suggest that modulation of adenosine receptor activity could increase the regenerative phase in these disorders by increasing the proliferation and differentiation rates of damaged tissue.

Key words: Adenosine A2A receptor, cardiovascular disorders, COVID-19, thrombosis.


 
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How to Cite this Article
Pubmed Style

Atif M, Alsrhani A, Naz F, Haq I, Imran M, Khalid S. Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. RMJ. 2022; 47(2): 271-274.


Web Style

Atif M, Alsrhani A, Naz F, Haq I, Imran M, Khalid S. Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. https://www.rmj.org.pk/?mno=17707 [Access: May 20, 2022].


AMA (American Medical Association) Style

Atif M, Alsrhani A, Naz F, Haq I, Imran M, Khalid S. Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. RMJ. 2022; 47(2): 271-274.



Vancouver/ICMJE Style

Atif M, Alsrhani A, Naz F, Haq I, Imran M, Khalid S. Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. RMJ. (2022), [cited May 20, 2022]; 47(2): 271-274.



Harvard Style

Atif, M., Alsrhani, . A., Naz, . F., Haq, . I., Imran, . M. & Khalid, . S. (2022) Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. RMJ, 47 (2), 271-274.



Turabian Style

Atif, Muhammmad, Abdullah Alsrhani, Farrah Naz, Iahtisham-Ul- Haq, Muhammad Imran, and Sidra Khalid. 2022. Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. Rawal Medical Journal, 47 (2), 271-274.



Chicago Style

Atif, Muhammmad, Abdullah Alsrhani, Farrah Naz, Iahtisham-Ul- Haq, Muhammad Imran, and Sidra Khalid. "Role of adenosine receptors in cardiovascular disorders and novel corona virus infection." Rawal Medical Journal 47 (2022), 271-274.



MLA (The Modern Language Association) Style

Atif, Muhammmad, Abdullah Alsrhani, Farrah Naz, Iahtisham-Ul- Haq, Muhammad Imran, and Sidra Khalid. "Role of adenosine receptors in cardiovascular disorders and novel corona virus infection." Rawal Medical Journal 47.2 (2022), 271-274. Print.



APA (American Psychological Association) Style

Atif, M., Alsrhani, . A., Naz, . F., Haq, . I., Imran, . M. & Khalid, . S. (2022) Role of adenosine receptors in cardiovascular disorders and novel corona virus infection. Rawal Medical Journal, 47 (2), 271-274.








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