Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents

Zunera Tanveer; Muhammad Rafiq; Irfan Shahzad Sheikh; Hafiz Muhammad Ali; Muhammad Tauseef Asmat; Mohammad Zahid Mustafa

2025, Vol: 50, Issue: 4

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RMJ. 2025; 50(4): 886-888

Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents

Zunera Tanveer, Muhammad Rafiq, Irfan Shahzad Sheikh, Hafiz Muhammad Ali, Muhammad Tauseef Asmat, Mohammad Zahid Mustafa.

Abstract
Objective: To evaluate the hematological and inflammatory parameters in heroin addicted adolescents.
Methodology: In this cross-sectional study, 84 subjects, divided into three groups, Group1 (control, n=28), Group 2 (heroin-addicted adolescents on medication, n=28) and Group 3 (heroin addicted adolescents without treatment, n=28) were recruited. Hematological and inflammatory parameters were measured. Statistical analysis was performed by ANOVA using SPSS 23.
Results: Hemoglobin, red blood cell count, and lymphocyte levels were significantly lower in group 3 when compared with other groups. Similarly, platelet, neutrophil count, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio were also significantly higher in group 3.
Conclusion: Heroin addiction in adolescents altered the physiological status, which led to vulnerability to infections and systemic inflammation. Neuroinflammation altered the neuronal pathways, which may contribute to behavioral changes in adolescents.

Key words: Adolescents, heroin addiction, hematological parameters, inflammatory ratios.

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How to Cite this Article

Pubmed Style

Tanveer Z, Rafiq M, Sheikh IS, Ali HM, Asmat MT, Mustafa MZ. Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents. RMJ. 2025; 50(4): 886-888.

Web Style

Tanveer Z, Rafiq M, Sheikh IS, Ali HM, Asmat MT, Mustafa MZ. Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents. https://www.rmj.org.pk/?mno=267252 [Access: October 29, 2025].

AMA (American Medical Association) Style

Tanveer Z, Rafiq M, Sheikh IS, Ali HM, Asmat MT, Mustafa MZ. Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents. RMJ. 2025; 50(4): 886-888.

Vancouver/ICMJE Style

Tanveer Z, Rafiq M, Sheikh IS, Ali HM, Asmat MT, Mustafa MZ. Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents. RMJ. (2025), [cited October 29, 2025]; 50(4): 886-888.

Harvard Style

Tanveer, Z., Rafiq, . M., Sheikh, . I. S., Ali, . H. M., Asmat, . M. T. & Mustafa, . M. Z. (2025) Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents. RMJ, 50 (4), 886-888.

Turabian Style

Tanveer, Zunera, Muhammad Rafiq, Irfan Shahzad Sheikh, Hafiz Muhammad Ali, Muhammad Tauseef Asmat, and Mohammad Zahid Mustafa. 2025. Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents. Rawal Medical Journal, 50 (4), 886-888.

Chicago Style

Tanveer, Zunera, Muhammad Rafiq, Irfan Shahzad Sheikh, Hafiz Muhammad Ali, Muhammad Tauseef Asmat, and Mohammad Zahid Mustafa. "Evaluation of inflammatory ratios and haematological parameters alteration in heroin addicted adolescents." Rawal Medical Journal 50 (2025), 886-888.

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