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Original Research 
RMJ. 2021; 46(2): 327-330


Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach

Javed Ali Lakho, Aneela Taj, Shameem Bhatti, Mushtaque Ahmed Mangrio.

Abstract
Objective: To study the incidence, risk factors and frequency of cholelithiasis and cholecystitis in the population of district Khairpur, Pakistan.
Methodology: A population based study was conducted in Department of Histopathology, PAQSJIMS, Gambat, Khairpur from January 2017 to August, 2018. A total of 56 cholecystectomy patients were included in the study. Post-surgery, gallbladder specimens were analyzed for histopathological spectrum after H&E stain. Microscopic observations were recorded.
Results: Out of 56 samples, 19.65% were from male whereas 80.35% from females. Chronic cholelithiasis (1.68%), chronic cholecystitis (22.96%), chronic cholecystitis with cholelithiasis (6.16%) and chronic ulcerated cholecystitis (0.56%) were the most common diagnoses. 16.07% of the male and 57.14% of female patients were found to be suffering from chronic cholecystitis. Age group 36 to 45 years was more prone to the gall bladder disease. Dyspepsia (92.85%) was the most common symptom. Focal ulceration and accumulation of acute and chronic inflammatory cells were observed both beneath the epithelium and subepithelium of the gallbladder.
Conclusion: The histopathological spectrum of gallbladder after cholecystectomy in district khairpur was observed to be quite diverse. The most dominant diagnosis was chronic cholecystitis followed by chronic cholecystitis with chronic cholelithiasis and chronic cholelithiasis whereas the chronic ulcerated cholecystitis was rarely observed.

Key words: : Gallstones, chronic cholecystitis, histopathology.


 
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How to Cite this Article
Pubmed Style

JAL, Taj A, SB, Mangrio MA. Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. RMJ. 2021; 46(2): 327-330.


Web Style

JAL, Taj A, SB, Mangrio MA. Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. http://www.rmj.org.pk/?mno=71443 [Access: June 12, 2021].


AMA (American Medical Association) Style

JAL, Taj A, SB, Mangrio MA. Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. RMJ. 2021; 46(2): 327-330.



Vancouver/ICMJE Style

JAL, Taj A, SB, Mangrio MA. Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. RMJ. (2021), [cited June 12, 2021]; 46(2): 327-330.



Harvard Style

, J. A. L., Taj, . A., , . S. B. & Mangrio, . M. A. (2021) Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. RMJ, 46 (2), 327-330.



Turabian Style

, Javed Ali Lakho, Aneela Taj, Shameem Bhatti, and Mushtaque Ahmed Mangrio. 2021. Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. Rawal Medical Journal, 46 (2), 327-330.



Chicago Style

, Javed Ali Lakho, Aneela Taj, Shameem Bhatti, and Mushtaque Ahmed Mangrio. "Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach." Rawal Medical Journal 46 (2021), 327-330.



MLA (The Modern Language Association) Style

, Javed Ali Lakho, Aneela Taj, Shameem Bhatti, and Mushtaque Ahmed Mangrio. "Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach." Rawal Medical Journal 46.2 (2021), 327-330. Print.



APA (American Psychological Association) Style

, J. A. L., Taj, . A., , . S. B. & Mangrio, . M. A. (2021) Prevalence of gallbladder diseases at Khairpur, Pakistan: A histopathological approach. Rawal Medical Journal, 46 (2), 327-330.








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