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Original Research 
RMJ. 2021; 46(4): 862-865


Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard

Hasan Sardar Sadiq, Shoaib Ali, Habib Ullah, Sahira Aaraj, Aleena Khan, Malik Muhammad Atif.

Abstract
Objective: To determine the diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein (CRP) for diagnosis of neonatal sepsis taking blood culture test as gold standard.
Methodology: This cross sectional study was conducted at Children Hospital, Lahore from 15-11-2019 to 15-6-2020 and included 201 neonates. Blood sample was collected for total leukocyte count, platelet count and CRP. Total leukocyte count >30000/mm3, <5000mm3, platelet count <100000/mm3 and CRP >10mg/L were considered diagnostic for neonatal sepsis.
Results: The mean age of neonates was 14.57±7.88 days; male to female ratio was 1.2:1. The sensitivity, specificity, & diagnostic accuracy of combination test were 77.59%, 92.94% & 84.08%, respectively taking blood culture as gold standard.
Conclusion: The combination of abnormal total leukocyte count, platelet count and CRP for diagnosis of neonatal sepsis is a reliable method.

Key words: Blood Culture, C-Reactive Protein, leukocyte count, neonatal sepsis, platelet count.


 
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How to Cite this Article
Pubmed Style

Sadiq HS, Ali S, Ullah H, Aaraj S, Khan A, Atif MM. Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. RMJ. 2021; 46(4): 862-865.

Web Style

Sadiq HS, Ali S, Ullah H, Aaraj S, Khan A, Atif MM. Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. http://www.rmj.org.pk/?mno=70930 [Access: October 14, 2021].

AMA (American Medical Association) Style

Sadiq HS, Ali S, Ullah H, Aaraj S, Khan A, Atif MM. Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. RMJ. 2021; 46(4): 862-865.


Vancouver/ICMJE Style

Sadiq HS, Ali S, Ullah H, Aaraj S, Khan A, Atif MM. Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. RMJ. (2021), [cited October 14, 2021]; 46(4): 862-865.


Harvard Style

Sadiq, H. S., Ali, . S., Ullah, . H., Aaraj, . S., Khan, . A. & Atif, . M. M. (2021) Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. RMJ, 46 (4), 862-865.


Turabian Style

Sadiq, Hasan Sardar, Shoaib Ali, Habib Ullah, Sahira Aaraj, Aleena Khan, and Malik Muhammad Atif. 2021. Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. Rawal Medical Journal, 46 (4), 862-865.


Chicago Style

Sadiq, Hasan Sardar, Shoaib Ali, Habib Ullah, Sahira Aaraj, Aleena Khan, and Malik Muhammad Atif. "Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard." Rawal Medical Journal 46 (2021), 862-865.


MLA (The Modern Language Association) Style

Sadiq, Hasan Sardar, Shoaib Ali, Habib Ullah, Sahira Aaraj, Aleena Khan, and Malik Muhammad Atif. "Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard." Rawal Medical Journal 46.4 (2021), 862-865. Print.


APA (American Psychological Association) Style

Sadiq, H. S., Ali, . S., Ullah, . H., Aaraj, . S., Khan, . A. & Atif, . M. M. (2021) Diagnostic accuracy of combination of abnormal total leukocyte count, platelet count and C-reactive protein for diagnosis of neonatal sepsis taking blood culture as gold standard. Rawal Medical Journal, 46 (4), 862-865.







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