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Original Research 
RMJ. 2021; 46(4): 880-883


Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure

Sadia Shafiq, Sadia Ghaffar, Qudsia Nawaz, Zubaida Shaheen, Farhan Iftikhar, Nazia Tufail.

Abstract
Objective: To compare the efficacy of low dose prostaglandin with high dose for induction of labor.
Methodology: This randomized control study was conducted in the Department of Obstetrics and Gynaecology, Jinnah Hospital, Lahore from January to June 2012. The sample size of 700 cases; 350 cases in each group was calculated with 5% significance level, 80% power of test and taking expected percentages of efficacy. Non-probability purposive sampling technique was used.
Results: We divided 700 patients into two equal groups. Patients of group A were given 1.5 mg Prostaglandin E2 (low dose) and group B 3 mg Prostaglandin E2 (high dose). Achievement of induction within Groups was found as 77.1% (270) in Group A while it was 85.4% (299) in Group B. Efficacy between two groups was found to be significant (X2=7.898, p<0.005). About 80% patients in age 21-30 years achieved vaginal deliveries out which 77%(174) were from Group A and 83.5% (167) from group B.
Conclusion: Low dose PGE2 was as efficacious as the high dose PGE2 vaginal tablets in inducing labor.

Key words: Cost-effective, induction, IOL, labor, Prostaglandin E2.


 
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How to Cite this Article
Pubmed Style

Shafiq S, Ghaffar S, Nawaz Q, Shaheen Z, Iftikhar F, Tufail N. Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. RMJ. 2021; 46(4): 880-883.


Web Style

Shafiq S, Ghaffar S, Nawaz Q, Shaheen Z, Iftikhar F, Tufail N. Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. http://www.rmj.org.pk/?mno=27836 [Access: October 14, 2021].


AMA (American Medical Association) Style

Shafiq S, Ghaffar S, Nawaz Q, Shaheen Z, Iftikhar F, Tufail N. Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. RMJ. 2021; 46(4): 880-883.



Vancouver/ICMJE Style

Shafiq S, Ghaffar S, Nawaz Q, Shaheen Z, Iftikhar F, Tufail N. Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. RMJ. (2021), [cited October 14, 2021]; 46(4): 880-883.



Harvard Style

Shafiq, S., Ghaffar, . S., Nawaz, . Q., Shaheen, . Z., Iftikhar, . F. & Tufail, . N. (2021) Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. RMJ, 46 (4), 880-883.



Turabian Style

Shafiq, Sadia, Sadia Ghaffar, Qudsia Nawaz, Zubaida Shaheen, Farhan Iftikhar, and Nazia Tufail. 2021. Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. Rawal Medical Journal, 46 (4), 880-883.



Chicago Style

Shafiq, Sadia, Sadia Ghaffar, Qudsia Nawaz, Zubaida Shaheen, Farhan Iftikhar, and Nazia Tufail. "Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure." Rawal Medical Journal 46 (2021), 880-883.



MLA (The Modern Language Association) Style

Shafiq, Sadia, Sadia Ghaffar, Qudsia Nawaz, Zubaida Shaheen, Farhan Iftikhar, and Nazia Tufail. "Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure." Rawal Medical Journal 46.4 (2021), 880-883. Print.



APA (American Psychological Association) Style

Shafiq, S., Ghaffar, . S., Nawaz, . Q., Shaheen, . Z., Iftikhar, . F. & Tufail, . N. (2021) Comparing the efficacy of low dose versus high dose PGE2 for IOL as a cost effective measure. Rawal Medical Journal, 46 (4), 880-883.








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