ISSN 0303-5212
 
2023, Vol: 48, Issue: 2
48 / 2Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Author certificate
Bank Reciept

Original Research 
RMJ. 2023; 48(3): 707-710


Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation

lubna Shaheen, Asim Mumtaz, Rehma Dar, Saadia Maqbool.

Abstract
Objective: To determine the reference values of beta hCG and PAPP-A among women aged 20– 40 years at 9-10 weeks of normal gestation.
Methodology: This descriptive observational study was conducted at Pathology Department of PGMI/Lahore General Hospital, Lahore from May, 2018 to June, 2020 and included 500 women at 9-10 weeks of gestation. Those with molar pregnancy, multiple pregnancies, threatened abortion, abnormal obstetric ultrasound findings, history of chronic diseases and smoking were excluded. Quantitative analysis of PAPP-A and β-hCG was performed on Backman Coulter Access 2 Immunoassay. Data was entered in SPSS version 21. Median and IQR were calculated for β-hCG and PAPP-A for total samples and in various subgroups of this population. Mann-Whitney U test and Kruskal-Wallis test were applied to find association between levels of β-HCG and PAPP-A with parity and age respectively.
Results: Out of 500 women, 214 (43%) were primigravida and 286 (57%) multigravidas. Mean age was 27.3±7.5 years. The median (IQR) values for β-hCG and PAPP-A were 53449.5(33322.5) mIU/ml and 425.10 (262.60) ng/ml, respectively. There was no significant association between levels of β-hCG and PAPP-A and parity. However, significant association was found between value of β-hCG and maternal age.
Conclusion: The median values of β-hCG and PAPP-A at 9-10 weeks of normal gestation were 53449.5 mIU/ml and 425.10 ng/ml, respectively. Significant association was found between value of β-hCG and maternal age.

Key words: PAPP-A, β-hCG, pregnancy, parity, reference.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by lubna Shaheen
Articles by Asim Mumtaz
Articles by Rehma Dar
Articles by Saadia Maqbool
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Shaheen l, Mumtaz A, Dar R, Maqbool S. Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. RMJ. 2023; 48(3): 707-710.

Web Style

Shaheen l, Mumtaz A, Dar R, Maqbool S. Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. https://www.rmj.org.pk/?mno=24586 [Access: September 03, 2023].

AMA (American Medical Association) Style

Shaheen l, Mumtaz A, Dar R, Maqbool S. Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. RMJ. 2023; 48(3): 707-710.


Vancouver/ICMJE Style

Shaheen l, Mumtaz A, Dar R, Maqbool S. Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. RMJ. (2023), [cited September 03, 2023]; 48(3): 707-710.


Harvard Style

Shaheen, l., Mumtaz, . A., Dar, . R. & Maqbool, . S. (2023) Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. RMJ, 48 (3), 707-710.


Turabian Style

Shaheen, lubna, Asim Mumtaz, Rehma Dar, and Saadia Maqbool. 2023. Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. Rawal Medical Journal, 48 (3), 707-710.


Chicago Style

Shaheen, lubna, Asim Mumtaz, Rehma Dar, and Saadia Maqbool. "Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation." Rawal Medical Journal 48 (2023), 707-710.


MLA (The Modern Language Association) Style

Shaheen, lubna, Asim Mumtaz, Rehma Dar, and Saadia Maqbool. "Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation." Rawal Medical Journal 48.3 (2023), 707-710. Print.


APA (American Psychological Association) Style

Shaheen, l., Mumtaz, . A., Dar, . R. & Maqbool, . S. (2023) Reference values of beta human chorionic gonadotrophin (β-hCG) and pregnancy associated placental protein-A (PAPP-A) among women aged 20–40 years at 9-10 weeks of normal gestation. Rawal Medical Journal, 48 (3), 707-710.


Author LoginReviewer LoginEditorial PoliciesConflict of Interest PolicyPlagiarism PolicyAdvertising Policy

About Rawal Medical Journal

Publication, subscription and Editorial office PMA House G/220-B Liaquat Road, Rawalpindi. Phone: 051-555-9812, Fax: 051-553-7088 Email: drnkhokhar@ya ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information