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2025, Vol: 50, Issue: 4
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Original Research 
RMJ. 2025; 50(3): 610-614


Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis

Muhammad Ali, Mahjabeen Yaseen, Saba Aziz, Ayesha Aijaz, Abdul Manan Junejo, Hina Iram.


Abstract
Objective: To assess the frequency of hepatitis-c reinfection after treatment with direct-acting antiviral (DAA) therapy undergoing maintenance hemodialysis.
Methodology: This observational, cross-sectional study included 160 patients in the Department of Nephrology, JPMC, from November 2019 to October 2020. The sampling technique used was non-probability. Demographic information, such as age, gender, HCV genotype, HCV RNA, and comorbidities, was gathered from the medical data or by interviews with patients and family members.
Results: The severity of liver disease was classified according to the Child-Turcotte-Pugh (CTP) score. We found that 38.9% patients had an average score of 6, and 53.7% were classified in CTP class A. The re-infection rate of HCV was very low after treatment with DAA.
Conclusion: DAAs have become a successful treatment for HCV, allowing the virus to be eradicated.

Key words: Reinfection, hepatitis c, Sofosbuvir, hemodialysis, virological response.


 
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How to Cite this Article
Pubmed Style

Ali M, Yaseen M, Aziz S, Aijaz A, Junejo AM, Iram H. Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. RMJ. 2025; 50(3): 610-614.

Web Style

Ali M, Yaseen M, Aziz S, Aijaz A, Junejo AM, Iram H. Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. https://www.rmj.org.pk/?mno=214498 [Access: October 29, 2025].

AMA (American Medical Association) Style

Ali M, Yaseen M, Aziz S, Aijaz A, Junejo AM, Iram H. Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. RMJ. 2025; 50(3): 610-614.


Vancouver/ICMJE Style

Ali M, Yaseen M, Aziz S, Aijaz A, Junejo AM, Iram H. Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. RMJ. (2025), [cited October 29, 2025]; 50(3): 610-614.


Harvard Style

Ali, M., Yaseen, . M., Aziz, . S., Aijaz, . A., Junejo, . A. M. & Iram, . H. (2025) Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. RMJ, 50 (3), 610-614.


Turabian Style

Ali, Muhammad, Mahjabeen Yaseen, Saba Aziz, Ayesha Aijaz, Abdul Manan Junejo, and Hina Iram. 2025. Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. Rawal Medical Journal, 50 (3), 610-614.


Chicago Style

Ali, Muhammad, Mahjabeen Yaseen, Saba Aziz, Ayesha Aijaz, Abdul Manan Junejo, and Hina Iram. "Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis." Rawal Medical Journal 50 (2025), 610-614.


MLA (The Modern Language Association) Style

Ali, Muhammad, Mahjabeen Yaseen, Saba Aziz, Ayesha Aijaz, Abdul Manan Junejo, and Hina Iram. "Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis." Rawal Medical Journal 50.3 (2025), 610-614. Print.


APA (American Psychological Association) Style

Ali, M., Yaseen, . M., Aziz, . S., Aijaz, . A., Junejo, . A. M. & Iram, . H. (2025) Frequency of hepatitis-c reinfection after treatment with direct-acting antiviral therapy undergoing maintenance hemodialysis. Rawal Medical Journal, 50 (3), 610-614.


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