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Original Research 
RMJ. 2024; 49(4): 730-733


Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients

Syed Zakir Shah, Aimal Khan, Hamayun Mumtaz, Iffat Naiyar, Muddasar Pervaiz, Waleed Bin Abdullah.


Abstract
Objective: To evaluate the neutrophil-lymphocyte ratio (NLR) as a predictor of inflammatory markers for diabetic nephropathy (DN) in type 2 diabetic patients.
Methodology: This descriptive observational study was conducted at medicine department of Pakistan Institute of Medical Sciences, Islamabad from 1st March 2021 to 1st Jan 2022). The non-probability convenience method of sampling was used for selecting patients aged 18 to 70 years belonging to both genders. HbA1C levels and microalbuminuria along with a CBC and RFTs were performed from the hospital laboratory. Microalbuminuria and N/L ratio were determined.
Results: Out of 200 subjects, 92 were found to be diagnosed with DN and 108 had normal renal function. T-test indicated the statistical relevance of NLR to DN subjects, however, there was no intergroup difference in individual TLC count. On the other hand, inter-group statistical relevance was observed in absolute neutrophil count (ANC) and absolute lymphocyte count (ALC).
Conclusion: For its early detection of DN, NLR a predictor of inflammatory markers can serve as an important biomarker.

Key words: Glomerular filtration rate, diabetic kidney disease, neutrophil-to-Lymphocyte ratio, total lymphocyte count.


 
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How to Cite this Article
Pubmed Style

Shah SZ, Khan A, Mumtaz H, Naiyar I, Pervaiz M, Abdullah WB. Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. RMJ. 2024; 49(4): 730-733.

Web Style

Shah SZ, Khan A, Mumtaz H, Naiyar I, Pervaiz M, Abdullah WB. Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. https://www.rmj.org.pk/?mno=201182 [Access: November 16, 2024].

AMA (American Medical Association) Style

Shah SZ, Khan A, Mumtaz H, Naiyar I, Pervaiz M, Abdullah WB. Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. RMJ. 2024; 49(4): 730-733.


Vancouver/ICMJE Style

Shah SZ, Khan A, Mumtaz H, Naiyar I, Pervaiz M, Abdullah WB. Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. RMJ. (2024), [cited November 16, 2024]; 49(4): 730-733.


Harvard Style

Shah, S. Z., Khan, . A., Mumtaz, . H., Naiyar, . I., Pervaiz, . M. & Abdullah, . W. B. (2024) Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. RMJ, 49 (4), 730-733.


Turabian Style

Shah, Syed Zakir, Aimal Khan, Hamayun Mumtaz, Iffat Naiyar, Muddasar Pervaiz, and Waleed Bin Abdullah. 2024. Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. Rawal Medical Journal, 49 (4), 730-733.


Chicago Style

Shah, Syed Zakir, Aimal Khan, Hamayun Mumtaz, Iffat Naiyar, Muddasar Pervaiz, and Waleed Bin Abdullah. "Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients." Rawal Medical Journal 49 (2024), 730-733.


MLA (The Modern Language Association) Style

Shah, Syed Zakir, Aimal Khan, Hamayun Mumtaz, Iffat Naiyar, Muddasar Pervaiz, and Waleed Bin Abdullah. "Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients." Rawal Medical Journal 49.4 (2024), 730-733. Print.


APA (American Psychological Association) Style

Shah, S. Z., Khan, . A., Mumtaz, . H., Naiyar, . I., Pervaiz, . M. & Abdullah, . W. B. (2024) Assessment of new inflammatory marker for diabetic kidney disease in Type 2 Diabetic patients. Rawal Medical Journal, 49 (4), 730-733.


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