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RMJ. 2024; 49(4): 827-830


Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia

Muhsan Sultan, Ahsan Ali, Aftab Hussain, Syed Samee Uddin, Najm us Saqib, Raja Nand.


Abstract
Objective: To determine the effectiveness of ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia.
Methodology: This Quasi-experimental study was done in the department of Anesthesiology, CMH, Peshawar from Jan to Jun 2023. A total of 146 patients of both genders planned for lower limb and abdominal surgeries under subarachnoid (spinal) block were segregated into two separate groups. Group A patients received ketamine (0.5 mg/kg) infusion over 10 minutes and Group B patients received dexmedetomidine (0.5mcg/kg) infusion over same time interval just before subarachnoid block. All patients were observed for development of shivering till 45 minutes of intra-operative period. The efficacy of anti-shivering effects of both drugs was compared between study groups.
Results: Mean age of the patients was 35.28± 10.73 years in the study group A while 32.38±9.27 years in the study set B (p=0.082). Mean BMI was 29.278±5.05 Kg/m2 in group A while 28.32±4.64 Kg/m2 in group B (p=0.197). Initial body (core) temperature was 36.88±0.32 °C in group A while 36.81±0.24 °C in group B (p=0.121). Absence of shivering was appreciated in 42 (57.5%) subjects in Group A as compared to 56 (76.7%) patients in Group B (p=0.014).
Conclusion: Dexmedetomidine had superior efficacy compared to ketamine for the prophylaxis of shivering caused by spinal anesthesia.

Key words: Dexmedetomidine, ketamine, shivering, subarachnoid block.


 
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How to Cite this Article
Pubmed Style

Sultan M, Ali A, Hussain A, Uddin SS, Saqib Nu, Nand R. Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. RMJ. 2024; 49(4): 827-830.

Web Style

Sultan M, Ali A, Hussain A, Uddin SS, Saqib Nu, Nand R. Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. https://www.rmj.org.pk/?mno=186543 [Access: November 17, 2024].

AMA (American Medical Association) Style

Sultan M, Ali A, Hussain A, Uddin SS, Saqib Nu, Nand R. Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. RMJ. 2024; 49(4): 827-830.


Vancouver/ICMJE Style

Sultan M, Ali A, Hussain A, Uddin SS, Saqib Nu, Nand R. Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. RMJ. (2024), [cited November 17, 2024]; 49(4): 827-830.


Harvard Style

Sultan, M., Ali, . A., Hussain, . A., Uddin, . S. S., Saqib, . N. u. & Nand, . R. (2024) Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. RMJ, 49 (4), 827-830.


Turabian Style

Sultan, Muhsan, Ahsan Ali, Aftab Hussain, Syed Samee Uddin, Najm us Saqib, and Raja Nand. 2024. Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. Rawal Medical Journal, 49 (4), 827-830.


Chicago Style

Sultan, Muhsan, Ahsan Ali, Aftab Hussain, Syed Samee Uddin, Najm us Saqib, and Raja Nand. "Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia." Rawal Medical Journal 49 (2024), 827-830.


MLA (The Modern Language Association) Style

Sultan, Muhsan, Ahsan Ali, Aftab Hussain, Syed Samee Uddin, Najm us Saqib, and Raja Nand. "Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia." Rawal Medical Journal 49.4 (2024), 827-830. Print.


APA (American Psychological Association) Style

Sultan, M., Ali, . A., Hussain, . A., Uddin, . S. S., Saqib, . N. u. & Nand, . R. (2024) Ketamine versus dexmedetomidine for prophylaxis of shivering caused by spinal anesthesia. Rawal Medical Journal, 49 (4), 827-830.


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