ISSN 0303-5212
 

Original Research
Online Published: 19 Sep 2026
 
RMJ. 2026; 51(4): 1093-1096


Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries

Syed Kumail Agha, Saleem Ahmed, Ayesha Shahid, Allah Ditta Ashfaq, Tanzeel Fatima, Syed Fazal E Karim Faisal.


Abstract
Objective: To compare the efficacy of two different thoracic epidural bupivacaine concentrations 0.0625% vs bupivacaine 0.125% in terms of pain control and analgesia required for cancer patients undergoing abdominal surgeries
Methodology: This study was done at the Department of Anesthesia, Shaukat Khanum Memorial Cancer Hospital, Lahore, and PAF Hospital, Islamabad from 1st September 2023 to 31st January 2024. We recruited 64 (32 in each group) patients undergoing abdominal surgery with a supraumbilical incision, and we randomly divided them into two groups. In group A, patients were given 0.0625% thoracic epidural bupivacaine. In group B, patients were given 0.125% thoracic epidural bupivacaine. After surgery, all the patients were followed up for 24 hours for pain score and analgesic requirements.
Results: At 24th hour, in 0.0625% bupivacaine group, the mean VAS score of was 4.34±1.28, and in 0.125% bupivacaine group, its mean value was 1.53±1.07 (p<0.001). At 24th hour, in 0.0625% bupivacaine group, analgesia requirement was noted in 32(100%) patients, and in 0.125% bupivacaine group it was noted in 28(87.5%) patients (p=0.11).
Conclusion: Epidural bupivacaine concentration 0.125% is better for pain control as compared to the bupivacaine concentration 0.0625%. So, bupivacaine concentration 0.125% should be employed for pain control in cancer patients having upper abdominal surgeries.

Key words: Abdominal surgeries, bupivacaine, cancer, epidural analgesia, postoperative pain.


 
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How to Cite this Article
Pubmed Style

Agha SK, Ahmed S, Shahid A, Ashfaq AD, Fatima T, Faisal SFEK. Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. RMJ. 2026; 51(4): 1093-1096.


Web Style

Agha SK, Ahmed S, Shahid A, Ashfaq AD, Fatima T, Faisal SFEK. Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. https://www.rmj.org.pk/?mno=287378 [Access: November 11, 2026].


AMA (American Medical Association) Style

Agha SK, Ahmed S, Shahid A, Ashfaq AD, Fatima T, Faisal SFEK. Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. RMJ. 2026; 51(4): 1093-1096.



Vancouver/ICMJE Style

Agha SK, Ahmed S, Shahid A, Ashfaq AD, Fatima T, Faisal SFEK. Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. RMJ. (2026), [cited November 11, 2026]; 51(4): 1093-1096.



Harvard Style

Agha, S. K., Ahmed, . S., Shahid, . A., Ashfaq, . A. D., Fatima, . T. & Faisal, . S. F. E. K. (2026) Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. RMJ, 51 (4), 1093-1096.



Turabian Style

Agha, Syed Kumail, Saleem Ahmed, Ayesha Shahid, Allah Ditta Ashfaq, Tanzeel Fatima, and Syed Fazal E Karim Faisal. 2026. Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. Rawal Medical Journal, 51 (4), 1093-1096.



Chicago Style

Agha, Syed Kumail, Saleem Ahmed, Ayesha Shahid, Allah Ditta Ashfaq, Tanzeel Fatima, and Syed Fazal E Karim Faisal. "Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries." Rawal Medical Journal 51 (2026), 1093-1096.



MLA (The Modern Language Association) Style

Agha, Syed Kumail, Saleem Ahmed, Ayesha Shahid, Allah Ditta Ashfaq, Tanzeel Fatima, and Syed Fazal E Karim Faisal. "Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries." Rawal Medical Journal 51.4 (2026), 1093-1096. Print.



APA (American Psychological Association) Style

Agha, S. K., Ahmed, . S., Shahid, . A., Ashfaq, . A. D., Fatima, . T. & Faisal, . S. F. E. K. (2026) Comparison of thoracic epidural bupivacaine 0.0625% vs bupivacaine 0.125% in cancer patients undergoing abdominal surgeries. Rawal Medical Journal, 51 (4), 1093-1096.