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Original Research 
RMJ. 2020; 45(3): 510-512


A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis

Ishtiaq Ishtiaq, Muhmmad Javaid Asad, Jamila, Muhammad Umer Khan, Tahira Tehseen, Rizwan Ahmed Kiani.

Abstract
Objective: To compare tuberculin skin test (TST) with T-Spot for diagnosis of active tuberculosis (TB) as well as latent tuberculosis infection (LTBI).
Methodology: This study was conducted at Department of Immunology, Islamabad diagnostic Center, Islamabad from January to December 2018. Blood Samples of 126 individuals for T SPOT and same patients were inoculated with PPD (Mantoux test).
Results: Among 126 participants, 64 (50.8%) were male and 62 (49.2%) were female. T-Spot. was positive in 52 (41.0%) while PPD was positive in 13 (10%). Furthermore, 25 (19.84%) T-Spot. TB test was positive for male while tuberculin skin test was positive in 6 (4.7%) male. T-Spot. was positive in 27 (21.4%) female while PPD was positive in 7 (5.5%). Additionally, one (0.79%) patient each of males and females was also found to be intermediate positive for PPD, which was clearly positive for T-Spot. TB test.
Conclusion: T-Spot. was much more sensitive and specific in all age groups and different clinical conditions including immune-compromised individuals. Skin test has limitation especially for older age groups but in T-Spot. is unaffected by age and provides excellent agreement.

Key words: Tuberclosis, IGRA, T Spot,tuberclin skin test


 
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How to Cite this Article
Pubmed Style

Ishtiaq I, Asad MJ, Jamila , Khan MU, Tehseen T, Kiani RA. A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. RMJ. 2020; 45(3): 510-512.

Web Style

Ishtiaq I, Asad MJ, Jamila , Khan MU, Tehseen T, Kiani RA. A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. https://www.rmj.org.pk/?mno=79462 [Access: December 07, 2023].

AMA (American Medical Association) Style

Ishtiaq I, Asad MJ, Jamila , Khan MU, Tehseen T, Kiani RA. A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. RMJ. 2020; 45(3): 510-512.


Vancouver/ICMJE Style

Ishtiaq I, Asad MJ, Jamila , Khan MU, Tehseen T, Kiani RA. A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. RMJ. (2020), [cited December 07, 2023]; 45(3): 510-512.


Harvard Style

Ishtiaq, I., Asad, . M. J., Jamila, ., Khan, . M. U., Tehseen, . T. & Kiani, . R. A. (2020) A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. RMJ, 45 (3), 510-512.


Turabian Style

Ishtiaq, Ishtiaq, Muhmmad Javaid Asad, Jamila, Muhammad Umer Khan, Tahira Tehseen, and Rizwan Ahmed Kiani. 2020. A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. Rawal Medical Journal, 45 (3), 510-512.


Chicago Style

Ishtiaq, Ishtiaq, Muhmmad Javaid Asad, Jamila, Muhammad Umer Khan, Tahira Tehseen, and Rizwan Ahmed Kiani. "A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis." Rawal Medical Journal 45 (2020), 510-512.


MLA (The Modern Language Association) Style

Ishtiaq, Ishtiaq, Muhmmad Javaid Asad, Jamila, Muhammad Umer Khan, Tahira Tehseen, and Rizwan Ahmed Kiani. "A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis." Rawal Medical Journal 45.3 (2020), 510-512. Print.


APA (American Psychological Association) Style

Ishtiaq, I., Asad, . M. J., Jamila, ., Khan, . M. U., Tehseen, . T. & Kiani, . R. A. (2020) A comparative study between TSOPT TB and tuberculin skin test for the diagnosis of tuberculosis. Rawal Medical Journal, 45 (3), 510-512.


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