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Original Research 
RMJ. 2021; 46(3): 620-624


Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis

Sara Rafique, Shazia Nazar Askari, Muhammad Mansoor Majeed, Afshan Mehboob Khan, Sassi Kanwal, Faiza Abdul Sattar.

Abstract
Objective: To compare Interleukin-6 (IL-6) levels with severity of periodontitis and to find the association of Vitamin D Binding Protein (DBP) with Interleukin-6 (IL-6) in healthy controls and periodontitis cases.
Methods: This case control study was conducted at Dow University of Health Sciences (DUHS). Periodontal examination was performed according to the probe pocket depth (PPD) and clinical attachment loss (CAL). Serum IL-6 and DBP levels were measured by enzyme-linked immunosorbent assay (ELISA).
Results: Median serum levels of IL-6 were 12.5 (IQR=38.8), 3.5 (IQR=71) and 21.2 (IQR=70.5) ng/l. There was no significant difference in median of IL-6 levels with severity of periodontitis (p>0.05). Statistically significant correlation was observed between DBP and IL-6 levels in cases (r=0.76, p<0.01).
Conclusion: Although levels of serum IL-6 were not statistically significant with the severity of the periodontal disease among cases but a significantly strong positive correlation of DBP with IL-6 levels was observed in patients with periodontitis.

Key words: Periodontitis, serum, vitamin D Binding Protein.


 
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How to Cite this Article
Pubmed Style

Rafique S, Askari SN, Majeed MM, Khan AM, Kanwal S, Sattar FA. Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. RMJ. 2021; 46(3): 620-624.


Web Style

Rafique S, Askari SN, Majeed MM, Khan AM, Kanwal S, Sattar FA. Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. http://www.rmj.org.pk/?mno=6577 [Access: August 06, 2021].


AMA (American Medical Association) Style

Rafique S, Askari SN, Majeed MM, Khan AM, Kanwal S, Sattar FA. Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. RMJ. 2021; 46(3): 620-624.



Vancouver/ICMJE Style

Rafique S, Askari SN, Majeed MM, Khan AM, Kanwal S, Sattar FA. Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. RMJ. (2021), [cited August 06, 2021]; 46(3): 620-624.



Harvard Style

Rafique, S., Askari, . S. N., Majeed, . M. M., Khan, . A. M., Kanwal, . S. & Sattar, . F. A. (2021) Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. RMJ, 46 (3), 620-624.



Turabian Style

Rafique, Sara, Shazia Nazar Askari, Muhammad Mansoor Majeed, Afshan Mehboob Khan, Sassi Kanwal, and Faiza Abdul Sattar. 2021. Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. Rawal Medical Journal, 46 (3), 620-624.



Chicago Style

Rafique, Sara, Shazia Nazar Askari, Muhammad Mansoor Majeed, Afshan Mehboob Khan, Sassi Kanwal, and Faiza Abdul Sattar. "Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis." Rawal Medical Journal 46 (2021), 620-624.



MLA (The Modern Language Association) Style

Rafique, Sara, Shazia Nazar Askari, Muhammad Mansoor Majeed, Afshan Mehboob Khan, Sassi Kanwal, and Faiza Abdul Sattar. "Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis." Rawal Medical Journal 46.3 (2021), 620-624. Print.



APA (American Psychological Association) Style

Rafique, S., Askari, . S. N., Majeed, . M. M., Khan, . A. M., Kanwal, . S. & Sattar, . F. A. (2021) Association of Vitamin D Binding Protein with Interleukin-6 levels in serum of patients with periodontitis. Rawal Medical Journal, 46 (3), 620-624.








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