ISSN 0303-5212
 

Original Research
Online Published: 23 Apr 2014
 
RMJ. 2014; 39(2): 119-123


Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients

Shumaila Khero, Muhammad Tanveer Alam, Muhammad Aurangzeb, Tazeen Rasheed, Zunaira Nawaz, Mehwish Fatima Jaffery, Muhammad Masroor.


Abstract
Introduction: Hepatic encephalopathy (HE) is a brain disorder caused by chronic liver failure, particularly in alcoholics with cirrhosis, which results in cognitive, psychiatric, and motor impairments. In these patients, the number of functional liver cells is reduced, and some blood is diverted around the liver before toxins are removed. As a result, toxins such as ammonia and manganese can accumulate in the blood and enter the brain, where they can damage nerve cells and supporting cells called astrocytes.

Key words: Hepatic encephalopathy, CLD, Serum ammonia level


 
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How to Cite this Article
Pubmed Style

Khero S, Alam MT, Aurangzeb M, Rasheed T, Nawaz Z, Jaffery MF, Masroor M. Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. RMJ. 2014; 39(2): 119-123.


Web Style

Khero S, Alam MT, Aurangzeb M, Rasheed T, Nawaz Z, Jaffery MF, Masroor M. Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. https://www.rmj.org.pk/?mno=44508 [Access: October 30, 2025].


AMA (American Medical Association) Style

Khero S, Alam MT, Aurangzeb M, Rasheed T, Nawaz Z, Jaffery MF, Masroor M. Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. RMJ. 2014; 39(2): 119-123.



Vancouver/ICMJE Style

Khero S, Alam MT, Aurangzeb M, Rasheed T, Nawaz Z, Jaffery MF, Masroor M. Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. RMJ. (2014), [cited October 30, 2025]; 39(2): 119-123.



Harvard Style

Khero, S., Alam, . M. T., Aurangzeb, . M., Rasheed, . T., Nawaz, . Z., Jaffery, . M. F. & Masroor, . M. (2014) Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. RMJ, 39 (2), 119-123.



Turabian Style

Khero, Shumaila, Muhammad Tanveer Alam, Muhammad Aurangzeb, Tazeen Rasheed, Zunaira Nawaz, Mehwish Fatima Jaffery, and Muhammad Masroor. 2014. Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. Rawal Medical Journal, 39 (2), 119-123.



Chicago Style

Khero, Shumaila, Muhammad Tanveer Alam, Muhammad Aurangzeb, Tazeen Rasheed, Zunaira Nawaz, Mehwish Fatima Jaffery, and Muhammad Masroor. "Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients." Rawal Medical Journal 39 (2014), 119-123.



MLA (The Modern Language Association) Style

Khero, Shumaila, Muhammad Tanveer Alam, Muhammad Aurangzeb, Tazeen Rasheed, Zunaira Nawaz, Mehwish Fatima Jaffery, and Muhammad Masroor. "Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients." Rawal Medical Journal 39.2 (2014), 119-123. Print.



APA (American Psychological Association) Style

Khero, S., Alam, . M. T., Aurangzeb, . M., Rasheed, . T., Nawaz, . Z., Jaffery, . M. F. & Masroor, . M. (2014) Co-relation of high serum ammonia levels with severity of hepatic encephalopathy in chronic liver disease patients. Rawal Medical Journal, 39 (2), 119-123.