ISSN 0303-5212
 
2026, Vol: 51, Issue: 1
51 / 1Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Author_Certificate
Bank Reciept

Original Research 
RMJ. 2026; 51(1): 156-159


Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus

Kainat Ayub Kullachi, Memuna, Hafiza Umm E Ammara, Muhammad Hannan Jamil, Khalid Rafique, Tahir Shaukat.


Abstract
Objective: To test the efficacy of Itone herbal eye drops compared to Hylo eye drops in increasing the tear film stability of patients with mild to moderate cases of Keratoconus.
Methodology: This quasi-experimental study was conducted at the Teaching Hospital, University of Lahore from April to August 2025. Purposive sampling was used to select 38 patients (76 eyes) with mild to moderate severity of keratoconus (K readings: 48–54 D) aged 15–35 years. Patients with severe keratoconus, other ocular/systemic pathology, or undergone ocular surgery previously or were under medication that influences the tear film were excluded. The sample was split into two groups (one was treated with Hylo eyedrops, and another with Itone herbal eyedrops), both administered three times a day. The data were analyzed by SPSS 26 with the help of the Wilcoxon and Mann-Whitney U tests.
Results: Out of the 38 participants, 21 (55.3%) were male and 17 (44.7) were female, with a mean age of 26±4.26 years (range: 18-34 years). Within the Itone group, the mean Ocular Surface Disease Index (OSDI) score dropped to 12.29±1.39 (range: 10.00-18.00) with two weeks of treatment as compared to the baseline level of 30.13 and 2.60 (range: 25.00-36.00) (p<0.001). The mean OSDI score of the Hylo group was also reduced significantly (31.08±3.78) to 20.21±1.71 (p<0.001).
Conclusion: Itone and Hylo were both effective eye drops that can be used in the treatment of dry eyes in patients with keratoconus.

Key words: Keratoconus, tear film, tear break up time, ocular surface disease index, artificial tears.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Kainat Ayub Kullachi
Articles by Memuna
Articles by Hafiza Umm E Ammara
Articles by Muhammad Hannan Jamil
Articles by Khalid Rafique
Articles by Tahir Shaukat
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Kullachi KA, Memuna , Ammara HUE, Jamil MH, Rafique K, Shaukat T. Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. RMJ. 2026; 51(1): 156-159.

Web Style

Kullachi KA, Memuna , Ammara HUE, Jamil MH, Rafique K, Shaukat T. Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. https://www.rmj.org.pk/?mno=284919 [Access: February 21, 2026].

AMA (American Medical Association) Style

Kullachi KA, Memuna , Ammara HUE, Jamil MH, Rafique K, Shaukat T. Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. RMJ. 2026; 51(1): 156-159.


Vancouver/ICMJE Style

Kullachi KA, Memuna , Ammara HUE, Jamil MH, Rafique K, Shaukat T. Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. RMJ. (2026), [cited February 21, 2026]; 51(1): 156-159.


Harvard Style

Kullachi, K. A., Memuna, ., Ammara, . H. U. E., Jamil, . M. H., Rafique, . K. & Shaukat, . T. (2026) Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. RMJ, 51 (1), 156-159.


Turabian Style

Kullachi, Kainat Ayub, Memuna, Hafiza Umm E Ammara, Muhammad Hannan Jamil, Khalid Rafique, and Tahir Shaukat. 2026. Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. Rawal Medical Journal, 51 (1), 156-159.


Chicago Style

Kullachi, Kainat Ayub, Memuna, Hafiza Umm E Ammara, Muhammad Hannan Jamil, Khalid Rafique, and Tahir Shaukat. "Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus." Rawal Medical Journal 51 (2026), 156-159.


MLA (The Modern Language Association) Style

Kullachi, Kainat Ayub, Memuna, Hafiza Umm E Ammara, Muhammad Hannan Jamil, Khalid Rafique, and Tahir Shaukat. "Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus." Rawal Medical Journal 51.1 (2026), 156-159. Print.


APA (American Psychological Association) Style

Kullachi, K. A., Memuna, ., Ammara, . H. U. E., Jamil, . M. H., Rafique, . K. & Shaukat, . T. (2026) Novel insights into the efficacy of Itone Vs. Hylo eye drops in tear film instability of keratoconus. Rawal Medical Journal, 51 (1), 156-159.


Author LoginReviewer LoginEditorial PoliciesConflict of Interest PolicyPlagiarism PolicyAdvertising Policy

About Rawal Medical Journal

Publication, subscription and Editorial office PMA House G/220-B Liaquat Road, Rawalpindi. Phone: 051-555-9812, Fax: 051-553-7088 Email: drnkhokhar@ya ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information