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Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia

Wita Saraswati, Pungky Mulawardhana, Tri Wulanhandarini, Rachmania Oktaviani.


Abstract
Objective: To compare D-Dimer levels between hysterectomy patients due to benign and malignant lesions and evaluate the relationship between postoperative D-Dimer levels with bleeding volume, duration of surgery, and tumor classification.
Methods: This analytical observational study involved 40 patients who underwent hysterectomy at Dr. Soetomo Hospital and Airlangga University Hospital Surabaya. D-Dimer examination was performed before surgery and 7–10 days after surgery. Data were analyzed with appropriate statistical tests using SPSS version 25.

Results: The mean preoperative D-Dimer levels in the benign and malignant groups were 1139.5 ng/mL and 952.8 ng/mL, respectively; postoperatively 1016.1 ng/mL and 869.4 ng/mL. There was no significant difference between the two groups (p>0.05). In addition, there was no significant relationship between postoperative D-Dimer levels and the amount of bleeding, duration of surgery, or tumor classification (p>0.05).
Conclusion: There was no significant difference in D-Dimer levels between patients with benign and malignant lesions after hysterectomy, and there was no relationship between postoperative D-Dimer levels and bleeding volume, duration of surgery, or tumor classification.

Key words: Hysterectomy, D-Dimer, venous thrombosis.


 
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How to Cite this Article
Pubmed Style

Saraswati W, Mulawardhana P, Wulanhandarini T, Oktaviani R. Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. RMJ. 2025; 50(4): 996-999. doi:10.5455/rmj.20250703055545

Web Style

Saraswati W, Mulawardhana P, Wulanhandarini T, Oktaviani R. Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. https://www.rmj.org.pk/?mno=268538 [Access: October 30, 2025]. doi:10.5455/rmj.20250703055545

AMA (American Medical Association) Style

Saraswati W, Mulawardhana P, Wulanhandarini T, Oktaviani R. Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. RMJ. 2025; 50(4): 996-999. doi:10.5455/rmj.20250703055545


Vancouver/ICMJE Style

Saraswati W, Mulawardhana P, Wulanhandarini T, Oktaviani R. Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. RMJ. (2025), [cited October 30, 2025]; 50(4): 996-999. doi:10.5455/rmj.20250703055545


Harvard Style

Saraswati, W., Mulawardhana, . P., Wulanhandarini, . T. & Oktaviani, . R. (2025) Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. RMJ, 50 (4), 996-999. doi:10.5455/rmj.20250703055545


Turabian Style

Saraswati, Wita, Pungky Mulawardhana, Tri Wulanhandarini, and Rachmania Oktaviani. 2025. Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. Rawal Medical Journal, 50 (4), 996-999. doi:10.5455/rmj.20250703055545


Chicago Style

Saraswati, Wita, Pungky Mulawardhana, Tri Wulanhandarini, and Rachmania Oktaviani. "Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia." Rawal Medical Journal 50 (2025), 996-999. doi:10.5455/rmj.20250703055545


MLA (The Modern Language Association) Style

Saraswati, Wita, Pungky Mulawardhana, Tri Wulanhandarini, and Rachmania Oktaviani. "Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia." Rawal Medical Journal 50.4 (2025), 996-999. Print. doi:10.5455/rmj.20250703055545


APA (American Psychological Association) Style

Saraswati, W., Mulawardhana, . P., Wulanhandarini, . T. & Oktaviani, . R. (2025) Comparison of D-Dimer levels between hysterectomy patients due to benign and malignant lesions at Dr. Soetomo Hospital and Airlangga University Hospital, Surabaya, Indonesia. Rawal Medical Journal, 50 (4), 996-999. doi:10.5455/rmj.20250703055545


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