ISSN 0303-5212
 

Case Report
Online Published: 24 Aug 2026
 
RMJ. 2026; 51(4): 1194-1195


A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department

Tallat Najeeb, Saleem Ahmed, Abdul Hameed Bhatti, Muhammad Aazam, Khadija Leghari, Hira Faheem.


Abstract
Hyperimmunoglobulin E (Hyper-IgE) syndrome is a rare, primary immune deficiency syndrome that can show characteristic manifestations in the head and neck. This case describes an unusual presentation of hyper-Ig E syndrome. This highlights the importance of a multidisciplinary team in its management. In this remarkable presentation, the external auditory canal was hypertrophic and full of granulations, which were treated with silver nitrate and mitomycin.

Key words: hyper-IgE syndrome, job syndrome, primary immunodeficiency.


 
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How to Cite this Article
Pubmed Style

Najeeb T, Ahmed S, Bhatti AH, Aazam M, Leghari K, Faheem H. A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. RMJ. 2026; 51(4): 1194-1195.


Web Style

Najeeb T, Ahmed S, Bhatti AH, Aazam M, Leghari K, Faheem H. A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. https://www.rmj.org.pk/?mno=260587 [Access: November 11, 2026].


AMA (American Medical Association) Style

Najeeb T, Ahmed S, Bhatti AH, Aazam M, Leghari K, Faheem H. A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. RMJ. 2026; 51(4): 1194-1195.



Vancouver/ICMJE Style

Najeeb T, Ahmed S, Bhatti AH, Aazam M, Leghari K, Faheem H. A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. RMJ. (2026), [cited November 11, 2026]; 51(4): 1194-1195.



Harvard Style

Najeeb, T., Ahmed, . S., Bhatti, . A. H., Aazam, . M., Leghari, . K. & Faheem, . H. (2026) A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. RMJ, 51 (4), 1194-1195.



Turabian Style

Najeeb, Tallat, Saleem Ahmed, Abdul Hameed Bhatti, Muhammad Aazam, Khadija Leghari, and Hira Faheem. 2026. A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. Rawal Medical Journal, 51 (4), 1194-1195.



Chicago Style

Najeeb, Tallat, Saleem Ahmed, Abdul Hameed Bhatti, Muhammad Aazam, Khadija Leghari, and Hira Faheem. "A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department." Rawal Medical Journal 51 (2026), 1194-1195.



MLA (The Modern Language Association) Style

Najeeb, Tallat, Saleem Ahmed, Abdul Hameed Bhatti, Muhammad Aazam, Khadija Leghari, and Hira Faheem. "A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department." Rawal Medical Journal 51.4 (2026), 1194-1195. Print.



APA (American Psychological Association) Style

Najeeb, T., Ahmed, . S., Bhatti, . A. H., Aazam, . M., Leghari, . K. & Faheem, . H. (2026) A rare case of Hyper Ige Syndrome presenting in the otorhinolaryngological department. Rawal Medical Journal, 51 (4), 1194-1195.