ISSN 0303-5212
 

Original Research 
RMJ. 2025; 50(4): 956-960


Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns

Muhammad Asghar Ali, Ameer Ahmed, Muhammad Anwar.


Abstract
Objective: To explore the demographic, clinical, and microbiological patterns associated with neonatal sepsis.
Methodology: This cross-sectional study was conducted at Neonatal Intensive Care Unit (NICU) of Bahawal Victoria Hospital, Bahawalpur, Pakistan from July to December 2024. We analyzed neonates admitted to the NICU with suspected or confirmed sepsis. Demographic, clinical, and microbiological profile of studied neonates were documented. Data analysis was performed using SPSS version 26.
Results: Out of 214 neonates, 122 (57.0%) were boys. Mean age was 9.38±8.05 days. The mean weight was 2.26±0.88 kg. Blood culture was positive in 50 (23.4%) neonates. Out of 50 blood culture positive cases, Klebsiella 8 (16.0%), yeast candida 8 (16.0%), E. coli 6 (12.0%), and pseudomonas 6 (12.0%) were the most common etiological agents. Out of 50 blood cultures proven sepsis cases, 38 (76.0%) were late-onset while 12 (24.0%) had early-onset neonatal sepsis.
Conclusion: Late-onset sepsis was more common than early-onset in neonatal sepsis. Low birth weight and inadequate antenatal care were significant risk factors for neonatal sepsis. Gram-negative bacteria, especially Klebsiella and E. coli, were predominant.

Key words: E. coli, etiology, klebsiella, pseudomonas, sepsis.


 
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Pubmed Style

Ali MA, Ahmed A, Anwar M. Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. RMJ. 2025; 50(4): 956-960.


Web Style

Ali MA, Ahmed A, Anwar M. Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. https://www.rmj.org.pk/?mno=236301 [Access: October 30, 2025].


AMA (American Medical Association) Style

Ali MA, Ahmed A, Anwar M. Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. RMJ. 2025; 50(4): 956-960.



Vancouver/ICMJE Style

Ali MA, Ahmed A, Anwar M. Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. RMJ. (2025), [cited October 30, 2025]; 50(4): 956-960.



Harvard Style

Ali, M. A., Ahmed, . A. & Anwar, . M. (2025) Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. RMJ, 50 (4), 956-960.



Turabian Style

Ali, Muhammad Asghar, Ameer Ahmed, and Muhammad Anwar. 2025. Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. Rawal Medical Journal, 50 (4), 956-960.



Chicago Style

Ali, Muhammad Asghar, Ameer Ahmed, and Muhammad Anwar. "Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns." Rawal Medical Journal 50 (2025), 956-960.



MLA (The Modern Language Association) Style

Ali, Muhammad Asghar, Ameer Ahmed, and Muhammad Anwar. "Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns." Rawal Medical Journal 50.4 (2025), 956-960. Print.



APA (American Psychological Association) Style

Ali, M. A., Ahmed, . A. & Anwar, . M. (2025) Exploring neonatal sepsis: An analysis of demographic, clinical and microbiological patterns. Rawal Medical Journal, 50 (4), 956-960.