ISSN 0303-5212
 
2024, Vol: 49, Issue: 1
49 / 1Current Issue Online FirstArchiveAims and ScopeAbstracting & IndexingMost Accessed ArticlesMost Downloaded ArticlesMost Cited Articles
Required files to be uploaded

Author_ Certificate.docx
Bank Reciept

Original Research 
RMJ. 2016; 41(3): 291-294


Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool.

Abstract
Objectives: To determine the efficacy of vitamin K prophylaxis in prevention of antibiotic induced coagulopathy in children on long-term (10 days) antibiotic therapy.
Methodology: It was a randomized controlled trial conducted at Pediatric ward of Nawaz Sharif social security Hospital, Lahore, Pakistan over a period of six months from December 1, 2013 to May 31, 2014. A total of 60 patients were included in this study and were divided into two groups. Both groups were given ceftriaxone for 10; Group-A was given vitamin K, 5mg intravenously – single dose on day third of antibiotic therapy and Group-B served as control and vitamin K was not given.
Results: Mean age was 1.84±2.5 and 1.16±1.0 in group-A and B, respectively. Protime (PT) was within normal range in all patients (100.0%) of group A and 22 patients (73.3%) in group B. APTT was normal in all patients (100.0%) in group-A and 22 patients (73.3%) in group-B. Coagulopathy was prevented in all patients (100%) in group-A and in 22 patients (73.3%) in group-B. The difference between two groups was statistically significant.
Conclusion: PT and APTT should be monitored and Vitamin K should be administered to all patients on prolonged antibiotics to prevent coagulopathy. Patients under one year and with poor nutritional status are more susceptible to vitamin K deficiency and coagulopathy.

Key words: Vitamin K, coagulopathy, infection


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Tooba Riaz
Articles by Bushra Saeed
Articles by Jaweria Faisal
Articles by Aneela Shaheen
Articles by Saima Batool
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. RMJ. 2016; 41(3): 291-294.

Web Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. https://www.rmj.org.pk/?mno=225571 [Access: December 05, 2023].

AMA (American Medical Association) Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. RMJ. 2016; 41(3): 291-294.


Vancouver/ICMJE Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. RMJ. (2016), [cited December 05, 2023]; 41(3): 291-294.


Harvard Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool (2016) Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. RMJ, 41 (3), 291-294.


Turabian Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. 2016. Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. Rawal Medical Journal, 41 (3), 291-294.


Chicago Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. "Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy." Rawal Medical Journal 41 (2016), 291-294.


MLA (The Modern Language Association) Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool. "Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy." Rawal Medical Journal 41.3 (2016), 291-294. Print.


APA (American Psychological Association) Style

Tooba Riaz, Bushra Saeed, Jaweria Faisal, Aneela Shaheen, Saima Batool (2016) Importance of Vitamin K prophylaxis in prevention of antibiotic induced coagulopathy. Rawal Medical Journal, 41 (3), 291-294.


Author LoginReviewer LoginEditorial PoliciesConflict of Interest PolicyPlagiarism PolicyAdvertising Policy

About Rawal Medical Journal

Publication, subscription and Editorial office PMA House G/220-B Liaquat Road, Rawalpindi. Phone: 051-555-9812, Fax: 051-553-7088 Email: drnkhokhar@ya ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information