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Original Research
Online Published: 17 May 2016
 
RMJ. 2016; 41(2): 197-199


Wilms’ tumor; different histological patterns observed in local children of Pakistan

Qurat Ul Ain Javaid, Nadia Naseem, Malik Adeel Anwar, Abdul Hanan Nagi.


Abstract
Objective: To describe the different histological patterns of Wilm’s tumor in local children of Pakistan.
Methodology: Biopsies from fresh nephrectomy specimens and paraffin embedded blocks from different hospitals of Lahore were studied.
Results: Out of 50 patients, 66% were males and 34% were females, with male: female ratio of 2:1. Mean age was 4±2.01 years. The most common clinical presentation was abdominal mass, pain and hematuria. Most common site of tumor was left kidney (68%). No bilateral tumor was found. Most common histological subtype was triphasic (56%) followed by monophasic (only blastemal;38%), biphasic (6%) and teratoid variant of wilm’s tumor (2%) cases. 21 cases were limited to stage I (42%), 12 progressing in stage II (24%). However stage III had only 9 (18%) cases and 8 in stage IV (16%). There was no case in stage V.
Conclusion: Wilm’s tumor is a common childhood malignancy in Pakistan with most common triphasic histological pattern with predominant blastema component and most frequently patients were limited to stage 1.

Key words: Wilm’s tumor, Histological subtype, teratoid variant.


 
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How to Cite this Article
Pubmed Style

Javaid QUA, Naseem N, Anwar MA, Nagi AH. Wilms’ tumor; different histological patterns observed in local children of Pakistan. RMJ. 2016; 41(2): 197-199.

Web Style

Javaid QUA, Naseem N, Anwar MA, Nagi AH. Wilms’ tumor; different histological patterns observed in local children of Pakistan. https://www.rmj.org.pk/?mno=205056 [Access: October 30, 2025].

AMA (American Medical Association) Style

Javaid QUA, Naseem N, Anwar MA, Nagi AH. Wilms’ tumor; different histological patterns observed in local children of Pakistan. RMJ. 2016; 41(2): 197-199.


Vancouver/ICMJE Style

Javaid QUA, Naseem N, Anwar MA, Nagi AH. Wilms’ tumor; different histological patterns observed in local children of Pakistan. RMJ. (2016), [cited October 30, 2025]; 41(2): 197-199.


Harvard Style

Javaid, Q. U. A., Naseem, . N., Anwar, . M. A. & Nagi, . A. H. (2016) Wilms’ tumor; different histological patterns observed in local children of Pakistan. RMJ, 41 (2), 197-199.


Turabian Style

Javaid, Qurat Ul Ain, Nadia Naseem, Malik Adeel Anwar, and Abdul Hanan Nagi. 2016. Wilms’ tumor; different histological patterns observed in local children of Pakistan. Rawal Medical Journal, 41 (2), 197-199.


Chicago Style

Javaid, Qurat Ul Ain, Nadia Naseem, Malik Adeel Anwar, and Abdul Hanan Nagi. "Wilms’ tumor; different histological patterns observed in local children of Pakistan." Rawal Medical Journal 41 (2016), 197-199.


MLA (The Modern Language Association) Style

Javaid, Qurat Ul Ain, Nadia Naseem, Malik Adeel Anwar, and Abdul Hanan Nagi. "Wilms’ tumor; different histological patterns observed in local children of Pakistan." Rawal Medical Journal 41.2 (2016), 197-199. Print.


APA (American Psychological Association) Style

Javaid, Q. U. A., Naseem, . N., Anwar, . M. A. & Nagi, . A. H. (2016) Wilms’ tumor; different histological patterns observed in local children of Pakistan. Rawal Medical Journal, 41 (2), 197-199.


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