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Original Research
Online Published: 07 Feb 2016
 


Changes in cardiovascular indices during use of epinephrine in septoplasty

Mir Mohammad Taghi Mortazavi, Seyyed Javad Seyyed Toutounchi, Maarouf Ansari.


Abstract
Objective: To assess cardiovascular changes in the use of epinephrine in septoplasty as well as to achieve the optimal dilution of the epinephrine to minimize these changes.
Methodology: In a randomized clinical trial, 100 patients who were about to undergo septoplasty in Imam Reza hospital, Tabriz, Iran, were randomly assigned to receive epinephrine with the dilution of 1:200,000 (group A) or lidocaine containing epinephrine with the dilution of 1:80,000 (group B). The changes in blood pressure, heart rate, and bleeding were compared between the two groups.
Results: There was no significant difference between the two groups in terms of gender, age, duration of operation, history of surgery on nasal septum, complications in previous surgeries, and the drugs used for anesthesia. However, the increase in blood pressure, and the bleeding in group A was significantly more than that in group B (14% vs. 2%). There was no significant difference between the two groups in terms of fluctuations in heart rate.
Conclusion: The use of lidocaine 2% with epinephrine 1:80,000 is preferable than the epinephrine 1:200,000 in terms of amount of bleeding and changes in blood pressure in septoplasty.

Key words: Septoplasty, epinephrine, lidocaine, blood pressure, heart rate, bleeding


 
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How to Cite this Article
Pubmed Style

Mortazavi MMT, Toutounchi SJS, Ansari M. Changes in cardiovascular indices during use of epinephrine in septoplasty. RMJ. 2016; 41(1): 86-89.

Web Style

Mortazavi MMT, Toutounchi SJS, Ansari M. Changes in cardiovascular indices during use of epinephrine in septoplasty. https://www.rmj.org.pk/?mno=187016 [Access: October 30, 2025].

AMA (American Medical Association) Style

Mortazavi MMT, Toutounchi SJS, Ansari M. Changes in cardiovascular indices during use of epinephrine in septoplasty. RMJ. 2016; 41(1): 86-89.


Vancouver/ICMJE Style

Mortazavi MMT, Toutounchi SJS, Ansari M. Changes in cardiovascular indices during use of epinephrine in septoplasty. RMJ. (2016), [cited October 30, 2025]; 41(1): 86-89.


Harvard Style

Mortazavi, M. M. T., Toutounchi, . S. J. S. & Ansari, . M. (2016) Changes in cardiovascular indices during use of epinephrine in septoplasty. RMJ, 41 (1), 86-89.


Turabian Style

Mortazavi, Mir Mohammad Taghi, Seyyed Javad Seyyed Toutounchi, and Maarouf Ansari. 2016. Changes in cardiovascular indices during use of epinephrine in septoplasty. Rawal Medical Journal, 41 (1), 86-89.


Chicago Style

Mortazavi, Mir Mohammad Taghi, Seyyed Javad Seyyed Toutounchi, and Maarouf Ansari. "Changes in cardiovascular indices during use of epinephrine in septoplasty." Rawal Medical Journal 41 (2016), 86-89.


MLA (The Modern Language Association) Style

Mortazavi, Mir Mohammad Taghi, Seyyed Javad Seyyed Toutounchi, and Maarouf Ansari. "Changes in cardiovascular indices during use of epinephrine in septoplasty." Rawal Medical Journal 41.1 (2016), 86-89. Print.


APA (American Psychological Association) Style

Mortazavi, M. M. T., Toutounchi, . S. J. S. & Ansari, . M. (2016) Changes in cardiovascular indices during use of epinephrine in septoplasty. Rawal Medical Journal, 41 (1), 86-89.


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