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Original Research
Online Published: 03 Nov 2015
 
RMJ. 2015; 40(4): 392-395


A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions

Humera Naz Altaaf, Fareeha Farooqui.


Abstract
Objective: To compare ultrasound guided fine-needle aspiration cytology (FNAC) and core needle biopsy (CNB) in patients presenting with palpable breast lumps (PBLs), in terms of sensitivity and specificity, taking final histopathology as gold standard.
Methodology: This cross-sectional study was conducted at Holy Family Hospital, Rawalpindi, Pakistan. Ultrasound guided FNAC and CNB were taken of all female patients with PBLs. The results were compared with final histopathology as gold standard. Data analysis was performed using SPSS software and chi-square test.
Results: A total of 60 patients were included in the study. The mean age was 33.8 yrs. The sensitivity and specificity of ultrasound guided FNAC were 68.7% and 93.1%, respectively. The sensitivity and specificity of ultrasound guided CNB was 93.7% and 100%. The accuracy of FNAC was 86.2% and that of core needle biopsy was 98.3%.
Conclusion: The ultrasound guided core needle biopsy can be used as an initial diagnostic test for the evaluation of all PBLs. Because of high negative predictive value core needle biopsy can replace surgical excision biopsy for benign lesions.

Key words: Breast lump, breast cancer, FNAC, Core needle biopsy


 
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Pubmed Style

Altaaf HN, Farooqui F. A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. RMJ. 2015; 40(4): 392-395.

Web Style

Altaaf HN, Farooqui F. A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. https://www.rmj.org.pk/?mno=183192 [Access: October 30, 2025].

AMA (American Medical Association) Style

Altaaf HN, Farooqui F. A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. RMJ. 2015; 40(4): 392-395.


Vancouver/ICMJE Style

Altaaf HN, Farooqui F. A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. RMJ. (2015), [cited October 30, 2025]; 40(4): 392-395.


Harvard Style

Altaaf, H. N. & Farooqui, . F. (2015) A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. RMJ, 40 (4), 392-395.


Turabian Style

Altaaf, Humera Naz, and Fareeha Farooqui. 2015. A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. Rawal Medical Journal, 40 (4), 392-395.


Chicago Style

Altaaf, Humera Naz, and Fareeha Farooqui. "A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions." Rawal Medical Journal 40 (2015), 392-395.


MLA (The Modern Language Association) Style

Altaaf, Humera Naz, and Fareeha Farooqui. "A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions." Rawal Medical Journal 40.4 (2015), 392-395. Print.


APA (American Psychological Association) Style

Altaaf, H. N. & Farooqui, . F. (2015) A comparison of ultrasound guided fine needle aspiration cytology and core needle biopsy in evaluation of palpable breast lesions. Rawal Medical Journal, 40 (4), 392-395.


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