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Original Research 
RMJ. 2024; 49(2): 310-313


Skin thickness and internal organ involvement in patients of systemic sclerosis

Fareheen Ashfaq, Humaira Talat, Faisal Ahmed, Maria Mansoor, Reema Mirza, Erum Ashraf.


Abstract
Objective: To elucidate the current magnitude of the internal organ/s involvement in patients of systemic sclerosis concerning their Modified Rondnan skin score (MRSS).
Methods: A total of 52 patients were included. Skin thickness was calculated by MRSS, and internal organ/s by history, examination, and investigations like serum creatinine, transthoracic echocardiography, HRCT and PFTs. Relation of skin thickness and internal organ involvement was studied. Data ware analyzed by SPSS version 24.0.
Results: Mean MRSS score was 19.4±10.53, female predominance (88.4%) and mean duration of 6.3±6.2 years The visceral involvement in patients with MRSS >20 showed greater visceral involvement. Isolated pulmonary involvement was recorded in 67.3% followed by pulmo-renal 11.5%, Pulmo-cardiac in 5.7% and pulmo-renal-cardiac in 9.6% of patients (p=0.001).
Conclusion: Our study showed the predominant involvement of pulmonary organs and the relation of MRSS with visceral involvement. The study emphasized the significance of MRSS as a non-invasive clinical tool for identifying high-risk patients at initial presentation.

Key words: High-resolution contrast tomography, interstitial lung disease, Modified Rodnan Skin Score, pulmonary function tests, systemic sclerosis.


 
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How to Cite this Article
Pubmed Style

Ashfaq F, Talat H, Ahmed F, Mansoor M, Mirza R, Ashraf E. Skin thickness and internal organ involvement in patients of systemic sclerosis. RMJ. 2024; 49(2): 310-313.

Web Style

Ashfaq F, Talat H, Ahmed F, Mansoor M, Mirza R, Ashraf E. Skin thickness and internal organ involvement in patients of systemic sclerosis. https://www.rmj.org.pk/?mno=160782 [Access: March 13, 2025].

AMA (American Medical Association) Style

Ashfaq F, Talat H, Ahmed F, Mansoor M, Mirza R, Ashraf E. Skin thickness and internal organ involvement in patients of systemic sclerosis. RMJ. 2024; 49(2): 310-313.


Vancouver/ICMJE Style

Ashfaq F, Talat H, Ahmed F, Mansoor M, Mirza R, Ashraf E. Skin thickness and internal organ involvement in patients of systemic sclerosis. RMJ. (2024), [cited March 13, 2025]; 49(2): 310-313.


Harvard Style

Ashfaq, F., Talat, . H., Ahmed, . F., Mansoor, . M., Mirza, . R. & Ashraf, . E. (2024) Skin thickness and internal organ involvement in patients of systemic sclerosis. RMJ, 49 (2), 310-313.


Turabian Style

Ashfaq, Fareheen, Humaira Talat, Faisal Ahmed, Maria Mansoor, Reema Mirza, and Erum Ashraf. 2024. Skin thickness and internal organ involvement in patients of systemic sclerosis. Rawal Medical Journal, 49 (2), 310-313.


Chicago Style

Ashfaq, Fareheen, Humaira Talat, Faisal Ahmed, Maria Mansoor, Reema Mirza, and Erum Ashraf. "Skin thickness and internal organ involvement in patients of systemic sclerosis." Rawal Medical Journal 49 (2024), 310-313.


MLA (The Modern Language Association) Style

Ashfaq, Fareheen, Humaira Talat, Faisal Ahmed, Maria Mansoor, Reema Mirza, and Erum Ashraf. "Skin thickness and internal organ involvement in patients of systemic sclerosis." Rawal Medical Journal 49.2 (2024), 310-313. Print.


APA (American Psychological Association) Style

Ashfaq, F., Talat, . H., Ahmed, . F., Mansoor, . M., Mirza, . R. & Ashraf, . E. (2024) Skin thickness and internal organ involvement in patients of systemic sclerosis. Rawal Medical Journal, 49 (2), 310-313.


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