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2023, Vol: 48, Issue: 2
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Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers

Abdulhalim S Serafi, Dina M. Qahwaji, Zahir Hussain, Mohammed A Bafail, Sumera Sohail.

Abstract
Objective: To determine the effect of the powder of Nigella sativa seeds (NSS) on serum low-density lipoprotein cholesterol (LDL-C) in female volunteers.
Methodology: This study included 159 female volunteers aged 30-35 years determe effect of various doses of Nigella sativa (NS) on LDL-C serum levels of eight groups for the duration of nine months. Subjects in the first month (October 2021) were considered as the control (C) subjects. Same subjects in the remaining eight months (November 2021 to June 2022) were administered equal daily doses (1 gram/day) of the powder of Kalonji/NSS. Blood samples were obtained and Friedewald formula was employed for determining the levels of serum LDL-C.
Results: The groups 1 to 8 altogether had significant decrease in LDL-C. Analysis of variance showed highly significant variations. Intergroup variations had p>0.0001. Various groups of LDL-C control range from 80-129.9 mg/dl under the influence of various doses of NS supplementation gave highly significant negative linear correlation.
Conclusion: Administration of NS showed the levels of LDL-C in the central range of 80-100 mg/dl that might be considered as the physiological normal serum levels of LDL-C. Further studies are required in healthy subjects and patients having various hyperlipidaemic and other related disorders to understand the diagnostic and therapeutic significance of NS.

Key words: Nigella sativa supplementation, Nigella sativa seeds, LDL cholesterol, healthy women volunteers.


 
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How to Cite this Article
Pubmed Style

Serafi AS, Qahwaji DM, Hussain Z, Bafail MA, Sohail S. Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. RMJ. 2023; 48(2): 526-530. doi:10.5455/rmj.20230213091322

Web Style

Serafi AS, Qahwaji DM, Hussain Z, Bafail MA, Sohail S. Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. https://www.rmj.org.pk/?mno=143701 [Access: August 16, 2023]. doi:10.5455/rmj.20230213091322

AMA (American Medical Association) Style

Serafi AS, Qahwaji DM, Hussain Z, Bafail MA, Sohail S. Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. RMJ. 2023; 48(2): 526-530. doi:10.5455/rmj.20230213091322


Vancouver/ICMJE Style

Serafi AS, Qahwaji DM, Hussain Z, Bafail MA, Sohail S. Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. RMJ. (2023), [cited August 16, 2023]; 48(2): 526-530. doi:10.5455/rmj.20230213091322


Harvard Style

Serafi, A. S., Qahwaji, . D. M., Hussain, . Z., Bafail, . M. A. & Sohail, . S. (2023) Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. RMJ, 48 (2), 526-530. doi:10.5455/rmj.20230213091322


Turabian Style

Serafi, Abdulhalim S, Dina M. Qahwaji, Zahir Hussain, Mohammed A Bafail, and Sumera Sohail. 2023. Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. Rawal Medical Journal, 48 (2), 526-530. doi:10.5455/rmj.20230213091322


Chicago Style

Serafi, Abdulhalim S, Dina M. Qahwaji, Zahir Hussain, Mohammed A Bafail, and Sumera Sohail. "Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers." Rawal Medical Journal 48 (2023), 526-530. doi:10.5455/rmj.20230213091322


MLA (The Modern Language Association) Style

Serafi, Abdulhalim S, Dina M. Qahwaji, Zahir Hussain, Mohammed A Bafail, and Sumera Sohail. "Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers." Rawal Medical Journal 48.2 (2023), 526-530. Print. doi:10.5455/rmj.20230213091322


APA (American Psychological Association) Style

Serafi, A. S., Qahwaji, . D. M., Hussain, . Z., Bafail, . M. A. & Sohail, . S. (2023) Nigella sativa supplementation normalizes serum LDL cholesterol in healthy women volunteers. Rawal Medical Journal, 48 (2), 526-530. doi:10.5455/rmj.20230213091322


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