Open Access and Peer-reviewed
Home Journal Issues Guide for Authors Editorial Board Aims & Scope About Journal News & Announcements


Original Research 
RMJ. 2022; 47(3): 585-588


The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan

Saeedunisa Sangi, Shabnum Naz Shaikh, Ahmed Bux Shaikh, Sumera Brohi, Shazia Shaikh, Shaista Hifaz Abro.

Abstract
Objective: To compare effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy.
Methodology: This randomized controlled trial was conducted at Chandka Medical College Larkana from May 2018 to May 2020. The enrollment criteria included all women between the ages of 18 and 45 years; symptomatic patients with Visual Analog Scale (VAS) scores >3 points; diagnosed with focal or diffuse adenomyosis; and post-operative histopathological confirmation of adenomyosis. We divided 150 patients in three groups having 50 patients in each group. In-group A GnRH was given, in-group B LNG-IUS was given and in Group C, no pharmacological treatment given postoperatively. All patients had regular three follow-up at two weekly intervals and VAS pain scores were recorded postoperatively and at each follow-up visit.
Results: VAS scores of all patients decreased from 7.0 (0.6) to 4 (0.3) at the 6 months, postoperatively. The postoperative VAS was significantly higher in-group C (no medical treatment) compared to group A and B, (p<0.05). Dysmenorrhea was noted in 24 (48.00%), 23 (46.00%), and 17 (34.00%) in Group A, B, and C, respectively which was significantly higher in group C.
Conclusion: The current study highlighted the significance of medical treatment with GnRH and LNG-IUS treatment following adenomyomectomy and recommend all patients be administered this to produce better patient outcome.

Key words: Adenomyosis, GnRH, LNG-IUS and Post adenomyomectomy.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Saeedunisa Sangi
Articles by Shabnum Naz Shaikh
Articles by Ahmed Bux Shaikh
Articles by Sumera Brohi
Articles by Shazia Shaikh
Articles by Shaista Hifaz Abro
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Sangi S, Shaikh SN, Shaikh AB, Brohi S, Shaikh S, Abro SH. The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. RMJ. 2022; 47(3): 585-588.


Web Style

Sangi S, Shaikh SN, Shaikh AB, Brohi S, Shaikh S, Abro SH. The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. https://www.rmj.org.pk/?mno=124870 [Access: September 02, 2022].


AMA (American Medical Association) Style

Sangi S, Shaikh SN, Shaikh AB, Brohi S, Shaikh S, Abro SH. The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. RMJ. 2022; 47(3): 585-588.



Vancouver/ICMJE Style

Sangi S, Shaikh SN, Shaikh AB, Brohi S, Shaikh S, Abro SH. The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. RMJ. (2022), [cited September 02, 2022]; 47(3): 585-588.



Harvard Style

Sangi, S., Shaikh, . S. N., Shaikh, . A. B., Brohi, . S., Shaikh, . S. & Abro, . S. H. (2022) The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. RMJ, 47 (3), 585-588.



Turabian Style

Sangi, Saeedunisa, Shabnum Naz Shaikh, Ahmed Bux Shaikh, Sumera Brohi, Shazia Shaikh, and Shaista Hifaz Abro. 2022. The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. Rawal Medical Journal, 47 (3), 585-588.



Chicago Style

Sangi, Saeedunisa, Shabnum Naz Shaikh, Ahmed Bux Shaikh, Sumera Brohi, Shazia Shaikh, and Shaista Hifaz Abro. "The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan." Rawal Medical Journal 47 (2022), 585-588.



MLA (The Modern Language Association) Style

Sangi, Saeedunisa, Shabnum Naz Shaikh, Ahmed Bux Shaikh, Sumera Brohi, Shazia Shaikh, and Shaista Hifaz Abro. "The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan." Rawal Medical Journal 47.3 (2022), 585-588. Print.



APA (American Psychological Association) Style

Sangi, S., Shaikh, . S. N., Shaikh, . A. B., Brohi, . S., Shaikh, . S. & Abro, . S. H. (2022) The effectiveness of pharmacological treatment for adenomyosis with GnRH and LNG-IUS post adenomyomectomy at Shaikh Zaid Woman Hospital Larkana Pakistan. Rawal Medical Journal, 47 (3), 585-588.








AUTHOR LOGIN

REVIEWER LOGIN

Indexed
&
Abstracted


Indexed in WHO Index Medicus IMEMR, Emromedex, Pakmedinet, ExtraMED,  Scopus, Web of Science and Tehqeeqat

                     Approved by the Higher Education Commission of Pakistan 


ABOUT JOURNAL
POLICIES
STATEMENTS

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.

The articles in Rawal Medical Journal are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.