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Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan

Noor Muhammad, Jehanzeb Afridi, Sajid Ali, Nourin Mehmood, Mahnoor Shoaib.

Abstract
Objective: To determine common coagulation disorders like abnormal prothrombin time/ international normalized ratio (PT/INR) abnormal activated partial thromboplastin time (aPTT), and decreased platelets count in patient with chronic liver disease (CLD).
Methodology: This study included 278 patients with CLD at Bilal Medical Trust and Hospital (BMTH) Pir Baba from January to October 2019. Bloods sample were collected in Ethylene diamine tetra acetic acid (EDTA), sodium citrate and plain vacutainer for Platelet’s count, PT and aPTT. These tests were performed using hematology and coagulation analyzers respectively. PT ratio was calculated along with INR ratio.
Results: Out of 278 patients, 23 (8.3%) had normal PT (less than 15 seconds), while 255 (91.7%) had prolonged PT (more than 15 seconds). aPTT were prolonged in 245 (88%) patients. 236 (84.89%) patients had both prolonged PT and aPTT. While 164 (64%) patients had low platelets count.
Conclusion: Most of the cirrhotic patients (more than 90%) were having abnormal pictures of the coagulation and even disturbed counts of low platelets.

Key words: HCV, Coagulation, PTAPTT, platelets, Bunir.


 
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How to Cite this Article
Pubmed Style

Muhammad N, Afridi J, Ali S, Mehmood N, Shoaib M. Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. RMJ. 2022; 47(1): 8-10.


Web Style

Muhammad N, Afridi J, Ali S, Mehmood N, Shoaib M. Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. https://www.rmj.org.pk/?mno=119198 [Access: April 05, 2022].


AMA (American Medical Association) Style

Muhammad N, Afridi J, Ali S, Mehmood N, Shoaib M. Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. RMJ. 2022; 47(1): 8-10.



Vancouver/ICMJE Style

Muhammad N, Afridi J, Ali S, Mehmood N, Shoaib M. Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. RMJ. (2022), [cited April 05, 2022]; 47(1): 8-10.



Harvard Style

Muhammad, N., Afridi, . J., Ali, . S., Mehmood, . N. & Shoaib, . M. (2022) Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. RMJ, 47 (1), 8-10.



Turabian Style

Muhammad, Noor, Jehanzeb Afridi, Sajid Ali, Nourin Mehmood, and Mahnoor Shoaib. 2022. Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. Rawal Medical Journal, 47 (1), 8-10.



Chicago Style

Muhammad, Noor, Jehanzeb Afridi, Sajid Ali, Nourin Mehmood, and Mahnoor Shoaib. "Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan." Rawal Medical Journal 47 (2022), 8-10.



MLA (The Modern Language Association) Style

Muhammad, Noor, Jehanzeb Afridi, Sajid Ali, Nourin Mehmood, and Mahnoor Shoaib. "Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan." Rawal Medical Journal 47.1 (2022), 8-10. Print.



APA (American Psychological Association) Style

Muhammad, N., Afridi, . J., Ali, . S., Mehmood, . N. & Shoaib, . M. (2022) Coagulation abnormalities in cirrhotic patients in district Bunir/Khyber Pakhtunkhwa, Pakistan. Rawal Medical Journal, 47 (1), 8-10.








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