ISSN 0303-5212
 

Original Research 


Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect

Haifa Ahmad Dasoky.

Abstract
Objective
To determine the clinical manifestation of congenital cytomegalovirus (CMV) infection and the effect of gancyclovir.
Methodology
Twenty newborns with congenital CMV infection were admitted at Queen Rania Hospital (KHMC) between January 2009 and December 2010 and were treated with Gancyclovir were included in the study.
Result
The most common clinical presentation was intrauterine growth retardation (45%), Hepatosplenomegaly (35%), Chorioretinites (35%) and purpuric skin rash (25%). Brain MRI was positive in 20%. Complete blood count was abnormal in 20%. More than 75% patients improved with gancyclovir without any complications.
Conclusion
Intrauterine growth retardation, hepatosplenomegaly and chorioretinites were commonest clinical manifestations of CMV infection. Gancyclovir was effective. Prevention of congenital CMV infection by immunization of symptomatic women who are at risk of primary infection during gestation should be emphasized. (Rawal Med J 2012;37:18-20).

Key words: Cytomegalovirus, gancyclovir, CMV.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Haifa Ahmad Dasoky
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

Haifa Ahmad Dasoky. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ. 2012; 37(1): 18-20.


Web Style

Haifa Ahmad Dasoky. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. https://www.rmj.org.pk/?mno=10844 [Access: December 06, 2023].


AMA (American Medical Association) Style

Haifa Ahmad Dasoky. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ. 2012; 37(1): 18-20.



Vancouver/ICMJE Style

Haifa Ahmad Dasoky. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ. (2012), [cited December 06, 2023]; 37(1): 18-20.



Harvard Style

Haifa Ahmad Dasoky (2012) Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. RMJ, 37 (1), 18-20.



Turabian Style

Haifa Ahmad Dasoky. 2012. Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. Rawal Medical Journal, 37 (1), 18-20.



Chicago Style

Haifa Ahmad Dasoky. "Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect." Rawal Medical Journal 37 (2012), 18-20.



MLA (The Modern Language Association) Style

Haifa Ahmad Dasoky. "Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect." Rawal Medical Journal 37.1 (2012), 18-20. Print.



APA (American Psychological Association) Style

Haifa Ahmad Dasoky (2012) Manifestation of symptomatic congenital cytomegalovirus infection and gancyclovir effect. Rawal Medical Journal, 37 (1), 18-20.