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Frequency of subclinical hypothyroidism in patients with chronic kidney disease

Rubina Ahmad, Nadia Saeed, Aziz Ahmed.

Abstract
Objective: To determine the frequency of subclinical hypothyroidism in patients with chronic kidney disease (CKD).
Methodology: It was a cross-sectional, observational study conducted at Internal Medicine and Nephrology Departments of Shifa International Hospital, Islamabad, from March 2016 to August 2016. A total of 90 adult patients with subclinical hypothyroidism (SCH) of both gender between ages 30-70 years with non-dialysis dependent CKD were enrolled. Their serum TSH and free T4 levels were measured.
Results: Out of 90 patients, 57(63.3 %) males and 33(36.7%) females. Mean age was 46.9±10.7 years. SCH was found in 19(21.1%) patients. The binary logistic analysis showed statistically significant relation of SCH with CKD stages 4 (p=0.04) and 5 (p=0.002) and insignificant relation with patients’ gender, age groups and CKD duration (P>0.05).
Conclusion: The frequency of SCH in our patients with established CKD was 21.1%. Multicenter studies should be conducted to further explore its prevalence and treatment effects in our population.

Key words: Subclinical hypothyroidism, chronic kidney disease, TSH


 
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How to Cite this Article
Pubmed Style

Ahmad R, Saeed N, Ahmed A. Frequency of subclinical hypothyroidism in patients with chronic kidney disease. RMJ. 2019; 44(1): 24-27.


Web Style

Ahmad R, Saeed N, Ahmed A. Frequency of subclinical hypothyroidism in patients with chronic kidney disease. http://www.rmj.org.pk/?mno=711 [Access: October 16, 2019].


AMA (American Medical Association) Style

Ahmad R, Saeed N, Ahmed A. Frequency of subclinical hypothyroidism in patients with chronic kidney disease. RMJ. 2019; 44(1): 24-27.



Vancouver/ICMJE Style

Ahmad R, Saeed N, Ahmed A. Frequency of subclinical hypothyroidism in patients with chronic kidney disease. RMJ. (2019), [cited October 16, 2019]; 44(1): 24-27.



Harvard Style

Ahmad, R., Saeed, . N. & Ahmed, . A. (2019) Frequency of subclinical hypothyroidism in patients with chronic kidney disease. RMJ, 44 (1), 24-27.



Turabian Style

Ahmad, Rubina, Nadia Saeed, and Aziz Ahmed. 2019. Frequency of subclinical hypothyroidism in patients with chronic kidney disease. Rawal Medical Journal, 44 (1), 24-27.



Chicago Style

Ahmad, Rubina, Nadia Saeed, and Aziz Ahmed. "Frequency of subclinical hypothyroidism in patients with chronic kidney disease." Rawal Medical Journal 44 (2019), 24-27.



MLA (The Modern Language Association) Style

Ahmad, Rubina, Nadia Saeed, and Aziz Ahmed. "Frequency of subclinical hypothyroidism in patients with chronic kidney disease." Rawal Medical Journal 44.1 (2019), 24-27. Print.



APA (American Psychological Association) Style

Ahmad, R., Saeed, . N. & Ahmed, . A. (2019) Frequency of subclinical hypothyroidism in patients with chronic kidney disease. Rawal Medical Journal, 44 (1), 24-27.








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