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2023, Vol: 48, Issue: 2
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Original Research 
RMJ. 2023; 48(3): 618-621


Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq

Heyam Qaid Muhammad AL-Kenani, Aqeel Abbas Kareem AL-Khafaji.

Abstract
Objective: To diagnose H. pylori infection and assess the likelihood of developing gastric cancer. It is necessary to describe instances and phenotypes of necroptosis in gastric cells.
Methodology: Fifty patients who had undergone gastrectomy from January 2020 to December 2022 were interviewed. A noninvasive investigation has been performed on each specimen to check for the presence of H. pylori by using stool, antibody test, urea breath test, and biopsy taken on endoscopy.
Results: Increased population of RIPK3-positive cells was observed in both gastric glands and lamina propria in H. pylori infected human oxyntic gastritis and atrophic specimens. Phenotypic analysis revealed that many RIPK3-positive cells were H + K+ ATPase-positive parietal cells in the gastric glands and are predominantly CD3-positive T lymphocytes CD68-positive macrophages, and SMA-alpha-positive stromal cells. Positive tests for H. pylori were conducted on 50 individuals on chemotherapy who already had gastric cancer as a consequence of exposure to bacteria. The incidence of stomach cancer was 62% in males and 38% in females with age between 30-85 years.
Conclusion: An increased population of RIPK3-positive cells was observed in several types of gastric cells. Future studies that define the effects and mechanisms developed of H. pylori disorders are needed.

Key words: H. pylori; gastric carcinoma; virulence and epidemiological factors, atrophy.


 
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Pubmed Style

AL-Kenani HQM, AL-Khafaji AAK. Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. RMJ. 2023; 48(3): 618-621.

Web Style

AL-Kenani HQM, AL-Khafaji AAK. Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. https://www.rmj.org.pk/?mno=153839 [Access: September 03, 2023].

AMA (American Medical Association) Style

AL-Kenani HQM, AL-Khafaji AAK. Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. RMJ. 2023; 48(3): 618-621.


Vancouver/ICMJE Style

AL-Kenani HQM, AL-Khafaji AAK. Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. RMJ. (2023), [cited September 03, 2023]; 48(3): 618-621.


Harvard Style

AL-Kenani, H. Q. M. & AL-Khafaji, . A. A. K. (2023) Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. RMJ, 48 (3), 618-621.


Turabian Style

AL-Kenani, Heyam Qaid Muhammad, and Aqeel Abbas Kareem AL-Khafaji. 2023. Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. Rawal Medical Journal, 48 (3), 618-621.


Chicago Style

AL-Kenani, Heyam Qaid Muhammad, and Aqeel Abbas Kareem AL-Khafaji. "Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq." Rawal Medical Journal 48 (2023), 618-621.


MLA (The Modern Language Association) Style

AL-Kenani, Heyam Qaid Muhammad, and Aqeel Abbas Kareem AL-Khafaji. "Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq." Rawal Medical Journal 48.3 (2023), 618-621. Print.


APA (American Psychological Association) Style

AL-Kenani, H. Q. M. & AL-Khafaji, . A. A. K. (2023) Co-relationship between Helicobacter pylori infection and patient of phenotype RIPK3 and gastric carcinoma in AL-Diywaniah Province, Iraq. Rawal Medical Journal, 48 (3), 618-621.


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