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Original Research 
RMJ. 2020; 45(2): 291-294


Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi

Abdul Sattar, Fatima Kaleem, Saleh Muhammad, Faisal Iqbal, M Qasim Zia, Rehan Anwar.

Abstract
Objective: To evaluate the current trend of antimicrobial susceptibility pattern of Salmonella typhi and paratyphi.
Methodology: This observational laboratory based study was conducted at Department of Microbiology, Khawaja Muhammad Safdar Medical College, Sialkot from January 1, to June 30, 2019. Blood culture samples were collected aseptically, sub cultured and identified as Samonella typhi or paratyphi A, as recommended by clinical laboratory standard institute.
Results: A total of 2773 samples were collected, among these 1945(70%) were from neonates and were excluded from the study. Among rest 828(30%) blood culture samples, 55(6.64%) yielded growth of Salmonella typhi and paratyphi. Out of total Salmonella species, 44(80%) were Salmonella typhi and 11(20%) were Salmonella Paratyphi A. Multidrug resistant salmonella were 47% and extensively drug resistant salmonella were 16%. Meropenem and azithromycin showed 100% sensitivity while ceftriaxone in 84% cases.
Conclusion: Trends of antibiotic susceptibility are changing as flouroquinolones are less effective than first line drugs. Extensively drug resistant cases of typhoid are also detected, which needs regular monitoring of sensitivity pattern.

Key words: Antibiotics,resistance, MDR salmonella, XDR salmonella.


 
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How to Cite this Article
Pubmed Style

Sattar A, Kaleem F, Muhammad S, Iqbal F, Zia MQ, Anwar R. Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. RMJ. 2020; 45(2): 291-294.


Web Style

Sattar A, Kaleem F, Muhammad S, Iqbal F, Zia MQ, Anwar R. Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. http://www.rmj.org.pk/?mno=78451 [Access: May 10, 2020].


AMA (American Medical Association) Style

Sattar A, Kaleem F, Muhammad S, Iqbal F, Zia MQ, Anwar R. Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. RMJ. 2020; 45(2): 291-294.



Vancouver/ICMJE Style

Sattar A, Kaleem F, Muhammad S, Iqbal F, Zia MQ, Anwar R. Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. RMJ. (2020), [cited May 10, 2020]; 45(2): 291-294.



Harvard Style

Sattar, A., Kaleem, . F., Muhammad, . S., Iqbal, . F., Zia, . M. Q. & Anwar, . R. (2020) Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. RMJ, 45 (2), 291-294.



Turabian Style

Sattar, Abdul, Fatima Kaleem, Saleh Muhammad, Faisal Iqbal, M Qasim Zia, and Rehan Anwar. 2020. Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. Rawal Medical Journal, 45 (2), 291-294.



Chicago Style

Sattar, Abdul, Fatima Kaleem, Saleh Muhammad, Faisal Iqbal, M Qasim Zia, and Rehan Anwar. "Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi." Rawal Medical Journal 45 (2020), 291-294.



MLA (The Modern Language Association) Style

Sattar, Abdul, Fatima Kaleem, Saleh Muhammad, Faisal Iqbal, M Qasim Zia, and Rehan Anwar. "Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi." Rawal Medical Journal 45.2 (2020), 291-294. Print.



APA (American Psychological Association) Style

Sattar, A., Kaleem, . F., Muhammad, . S., Iqbal, . F., Zia, . M. Q. & Anwar, . R. (2020) Current trends in antimicrobial susceptibility pattern of Salmonella typhi and paratyphi. Rawal Medical Journal, 45 (2), 291-294.








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