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Case Report Open Access
RMJ. 2017; 42(3): 432-434


A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis

Liyana Najwa Inche Mat, Wan Aliaa Wan Sulaiman, Hoo Fan Kee, Hakimah Sallehuddin, Hamidon Basri.

Abstract
Cerebral deep vein thrombosis is rare but it carries high morbidity and mortality. The mainstay of treatment is anticoagulation with vitamin K antagonist (VKA). However, VKA has a lot of drawback of fatal bleeding in Asian population, drug-drug and drug-food interactions and the need for frequent INR monitoring when compared to novel oral anticoagulants (NOACs). Here, we present a case of a 52-year-old lady who was admitted with 3 days history of a headache and confusion. Physical examinations revealed no long tract signs and blood investigations were normal. Thrombosis of the vein of Galen was diagnosed on MRI of the brain. We describe successful treatment with subcutaneous low molecular weight heparin for 2 weeks followed by oral direct thrombin inhibitor dabigatran.

Key words: Cerebral deep vein thrombosis, Vein of Galen, direct thrombin inhibitors.


 
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How to Cite this Article
Pubmed Style

Mat LNI, Sulaiman WAW, Kee HF, Sallehuddin H, Basri H. A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. RMJ. 2017; 42(3): 432-434.


Web Style

Mat LNI, Sulaiman WAW, Kee HF, Sallehuddin H, Basri H. A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. http://www.rmj.org.pk/?mno=258259 [Access: December 17, 2017].


AMA (American Medical Association) Style

Mat LNI, Sulaiman WAW, Kee HF, Sallehuddin H, Basri H. A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. RMJ. 2017; 42(3): 432-434.



Vancouver/ICMJE Style

Mat LNI, Sulaiman WAW, Kee HF, Sallehuddin H, Basri H. A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. RMJ. (2017), [cited December 17, 2017]; 42(3): 432-434.



Harvard Style

Mat, L. N. I., Sulaiman, W. A. W., Kee, H. F., Sallehuddin, H. & Basri, H. (2017) A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. RMJ, 42 (3), 432-434.



Turabian Style

Mat, Liyana Najwa Inche, Wan Aliaa Wan Sulaiman, Hoo Fan Kee, Hakimah Sallehuddin, and Hamidon Basri. 2017. A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. Rawal Medical Journal, 42 (3), 432-434.



Chicago Style

Mat, Liyana Najwa Inche, Wan Aliaa Wan Sulaiman, Hoo Fan Kee, Hakimah Sallehuddin, and Hamidon Basri. "A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis." Rawal Medical Journal 42 (2017), 432-434.



MLA (The Modern Language Association) Style

Mat, Liyana Najwa Inche, Wan Aliaa Wan Sulaiman, Hoo Fan Kee, Hakimah Sallehuddin, and Hamidon Basri. "A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis." Rawal Medical Journal 42.3 (2017), 432-434. Print.



APA (American Psychological Association) Style

Mat, L. N. I., Sulaiman, W. A. W., Kee, H. F., Sallehuddin, H. & Basri, H. (2017) A rare case of vein of Galen thrombosis: Exploring a potential role for novel oral anticoagulants (NOACs) in cerebral deep vein thrombosis. Rawal Medical Journal, 42 (3), 432-434.




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The articles in Rawal Medical Journal are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.