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Original Research 


Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients

Sherif S. Karawya, Neveen M. Sabra.


Abstract
Objective

To assess contrast sensitivity in relation to different Foveal Avascular Zone (FAZ) abnormalities in diabetic patients.

Method

Forty five diabetic patients underwent fluorescein angiography to study morphologic changes, namely FAZ diameter and regularity of perifoveal capillary network using mid phase frames. A grading scheme was used to study both features. Patients were classified into 3 groups according to FAZ morphologic features. Contrast sensitivity testing was done in all patients in four spatial frequencies (3, 6, 12 and 18 cycles/degree [c/deg]). The significance of difference between groups concerning contrast sensitivity values was assessed.

Results

Reduction of contrast sensitivity at 6 c/deg was significantly related to increased FAZ diameter (p=0.01), while reduction at 6 c/deg and 12 c/deg was significantly related to disturbed FAZ outline (p=0.002)

Conclusions

Contrast sensitivity could be a clinical adjunct in diagnosing early ischemic diabetic maculopathy. (Rawal Med J 2009; 34: 51-53).

Key words: Contrast sensitivity, diabetes, foveal avascularzone, ischemic maculopathy.


 
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How to Cite this Article
Pubmed Style

Karawya SS, Sabra NM. Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. RMJ. 2009; 34(1): 51-53.

Web Style

Karawya SS, Sabra NM. Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. https://www.rmj.org.pk/?mno=7217 [Access: October 30, 2025].

AMA (American Medical Association) Style

Karawya SS, Sabra NM. Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. RMJ. 2009; 34(1): 51-53.


Vancouver/ICMJE Style

Karawya SS, Sabra NM. Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. RMJ. (2009), [cited October 30, 2025]; 34(1): 51-53.


Harvard Style

Karawya, S. S. & Sabra, . N. M. (2009) Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. RMJ, 34 (1), 51-53.


Turabian Style

Karawya, Sherif S., and Neveen M. Sabra. 2009. Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. Rawal Medical Journal, 34 (1), 51-53.


Chicago Style

Karawya, Sherif S., and Neveen M. Sabra. "Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients." Rawal Medical Journal 34 (2009), 51-53.


MLA (The Modern Language Association) Style

Karawya, Sherif S., and Neveen M. Sabra. "Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients." Rawal Medical Journal 34.1 (2009), 51-53. Print.


APA (American Psychological Association) Style

Karawya, S. S. & Sabra, . N. M. (2009) Impact of morphologic changes of foveal avascular zone on contrast sensitivity in diabetic patients. Rawal Medical Journal, 34 (1), 51-53.


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