ISSN 0303-5212
 

Original Research 


Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan

Altaf Ahmed Shaikh, Anum Shaikh, Amber Tahir.

Abstract
Objective: To study the pattern of antimicrobial sensitivity to Salmonella Typhoid in Southern part of Pakistan.
Methodology: This retrospective analysis included all blood culture samples positive for Salmonella typhi, paratyphi A, and paratyphi B in adults of age >18 years seen at Ghulam Muhammad Mahar Medical College and Hospital, Sukkur from January to December 2017. Multidrug resistant (MDR) typhoid was defined as the strains resistant to all first line agents. Extended drug resistant (XDR) cases were taken as those resistant to all first line agents along with resistance to fluoroquinolones and ceftriaxone. Data were analyzed using SPSS version. 21.0
Results: Of 465 salmonella positive isolates, 69.4% were S. typhi, 20.6% were S. paratyphi A and 9.9% were S. paratyphi B. S. typhi was more common in males (52.6%). Among the S. typhi strains, ciprofloxacin showed highest resistance (62.5%); ceftriaxone showed a resistance of 20.7%. There were 17% MDR and 3.7% XDR strains of S. typhi.
Conclusion: There is alarming rise in antimicrobial resistance against Salmonellae in Pakistan. Surveillance studies must be used to monitor the typhoid spread and its evolving antimicrobial resistance.

Key words: Antibiotic resistance, typhoid, enteric fever, salmonella, Pakistan.


 
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Pubmed Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ. 2019; 44(1): 7-10.


Web Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. https://www.rmj.org.pk/?mno=22011 [Access: December 07, 2023].


AMA (American Medical Association) Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ. 2019; 44(1): 7-10.



Vancouver/ICMJE Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ. (2019), [cited December 07, 2023]; 44(1): 7-10.



Harvard Style

Shaikh, A. A., Shaikh, . A. & Tahir, . A. (2019) Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ, 44 (1), 7-10.



Turabian Style

Shaikh, Altaf Ahmed, Anum Shaikh, and Amber Tahir. 2019. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. Rawal Medical Journal, 44 (1), 7-10.



Chicago Style

Shaikh, Altaf Ahmed, Anum Shaikh, and Amber Tahir. "Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan." Rawal Medical Journal 44 (2019), 7-10.



MLA (The Modern Language Association) Style

Shaikh, Altaf Ahmed, Anum Shaikh, and Amber Tahir. "Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan." Rawal Medical Journal 44.1 (2019), 7-10. Print.



APA (American Psychological Association) Style

Shaikh, A. A., Shaikh, . A. & Tahir, . A. (2019) Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. Rawal Medical Journal, 44 (1), 7-10.