ISSN 0303-5212
 

Original Research 
RMJ. 2019; 44(3): 445-448


Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications

Farrah BILAL, Mudassar Iqbal ARAIN, Ubed Ur Rehman , Abdullah Dayo, Muhammad Ali Ghoto, Ahsan Ali Memon.

Abstract
Objective: To examine the antimicrobial therapy as prophylaxis and treatment of bacterial infection in liver diseases and its complications.
Methodology: This descriptive study was carried out at Liaquat University of medical and health sciences hospital Hyderabad, Pakistan from May to October 2018. Patients of liver cirrhosis with positive HCV antibodies, age from 16 to 70 years were included. Diagnosis of liver impairment was based on patient’s clinical features and laboratory tests which is documented in patient’s records. Purposive sampling technique was used to collect the data. Child Pugh classes are used to determine the severity and prognosis of disease.
Results: Out of 250 patients, 156(61.2%) were males and 48(38.8%) were females. 109(43.6%) belonged to Child Pugh Class C. Ascitic fluid analysis showed that 101(40.4%) samples were infected and 40.4% were culture positive. Escherichia coli was most frequent in 41(20.5%) organism. Most frequently ceftriaxone was prescribed intravenously in 121(48.4%) patients.
Conclusion: Bacterial peritonitis was widespread in liver disease. Ascites was a major problem and ascitic fluid culture showed E.coli as commonest causative agent of infections. Ceftriaxone was mostly used in them.

Key words: Bacterial peritonitis, Child Pugh class, prophylaxis, cirrhosis.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Farrah BILAL
Articles by Mudassar Iqbal ARAIN
Articles by Ubed Ur Rehman
Articles by Abdullah Dayo
Articles by Muhammad Ali Ghoto
Articles by Ahsan Ali Memon
on Google
on Google Scholar

How to Cite this Article
Pubmed Style

BILAL F, ARAIN MI, UUR, Dayo A, Ghoto MA, Memon AA, . Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. RMJ. 2019; 44(3): 445-448.


Web Style

BILAL F, ARAIN MI, UUR, Dayo A, Ghoto MA, Memon AA, . Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. https://www.rmj.org.pk/?mno=37759 [Access: December 05, 2023].


AMA (American Medical Association) Style

BILAL F, ARAIN MI, UUR, Dayo A, Ghoto MA, Memon AA, . Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. RMJ. 2019; 44(3): 445-448.



Vancouver/ICMJE Style

BILAL F, ARAIN MI, UUR, Dayo A, Ghoto MA, Memon AA, . Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. RMJ. (2019), [cited December 05, 2023]; 44(3): 445-448.



Harvard Style

BILAL, F. . ., ARAIN, M. I., , . U. U. R., Dayo, A., Ghoto, M. A., Memon, A. A. & (2019) Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. RMJ, 44 (3), 445-448.



Turabian Style

BILAL, Farrah , Mudassar Iqbal ARAIN, Ubed Ur Rehman, Abdullah Dayo, Muhammad Ali Ghoto, Ahsan Ali Memon, and . 2019. Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. Rawal Medical Journal, 44 (3), 445-448.



Chicago Style

BILAL, Farrah , Mudassar Iqbal ARAIN, Ubed Ur Rehman, Abdullah Dayo, Muhammad Ali Ghoto, Ahsan Ali Memon, and . "Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications." Rawal Medical Journal 44 (2019), 445-448.



MLA (The Modern Language Association) Style

BILAL, Farrah , Mudassar Iqbal ARAIN, Ubed Ur Rehman, Abdullah Dayo, Muhammad Ali Ghoto, Ahsan Ali Memon, and . "Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications." Rawal Medical Journal 44.3 (2019), 445-448. Print.



APA (American Psychological Association) Style

BILAL, F. . ., ARAIN, M. I., , . U. U. R., Dayo, A., Ghoto, M. A., Memon, A. A. & (2019) Utilization of antimicrobial agents for prophylaxis and treatment of bacterial infection in liver diseases and its complications. Rawal Medical Journal, 44 (3), 445-448.