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Original Research 
RMJ. 2020; 45(3): 593-597


Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers

Shahneela Siraj, Meraj Raheem, Durr e Sameen Kamran, Afshan Mehboob Khan, Naila Parveen, Masood Anwar Qureshi.

Abstract
Objective:To measure serum insulin levels and anthropometric indices of the macrosomic neonates and to associate them with maternal glycemic factors.
Methodology: This multi-center cross-sectional study was conducted in various hospitals in Karachi from November 2011 to February 2013 and included 125 macrosomic neonates. Mothers were grouped as diabetic and non-diabetics. Anthropometric parameters of babywere measured in addition to blood markers like cord blood insulin.
Results: Comparison of anthropometric indices showed statistically significant higher values of head circumference (p=0.007), chest circumference (p=0.015), abdominal circumference (p<0.010), mid-upper arm (p<0.010) and bi-parietal diameters (p=0.035) in macrosomic neonates of diabetic mothers as compared to macrosomic neonates of non-diabetic mothers. Fetal serum insulin was increased in neonates of diabetic mothers as compared to that of non-diabetics.
Conclusion:Hyperinsulinemia was found in increased frequency in macrosomic infants of diabetic mothers as compared to the non- diabetics. Newborns of diabetic mothers showed significantly higher bi-parietal diameter, head, chest, abdominal and mid upper arm circumference. Abdominal circumference and mid upper arm circumference were significantly high in the macrosomic infants with hyperinsulinemia.

Key words: Macrosomia, hyperinsulinemia, diabetes, anthropometric indices.


 
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How to Cite this Article
Pubmed Style

Siraj S, Raheem M, Kamran DeS, Khan AM, Parveen N, Qureshi MA. Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. RMJ. 2020; 45(3): 593-597.


Web Style

Siraj S, Raheem M, Kamran DeS, Khan AM, Parveen N, Qureshi MA. Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. http://www.rmj.org.pk/?mno=81494 [Access: September 02, 2020].


AMA (American Medical Association) Style

Siraj S, Raheem M, Kamran DeS, Khan AM, Parveen N, Qureshi MA. Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. RMJ. 2020; 45(3): 593-597.



Vancouver/ICMJE Style

Siraj S, Raheem M, Kamran DeS, Khan AM, Parveen N, Qureshi MA. Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. RMJ. (2020), [cited September 02, 2020]; 45(3): 593-597.



Harvard Style

Siraj, S., Raheem, . M., Kamran, . D. e. S., Khan, . A. M., Parveen, . N. & Qureshi, . M. A. (2020) Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. RMJ, 45 (3), 593-597.



Turabian Style

Siraj, Shahneela, Meraj Raheem, Durr e Sameen Kamran, Afshan Mehboob Khan, Naila Parveen, and Masood Anwar Qureshi. 2020. Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. Rawal Medical Journal, 45 (3), 593-597.



Chicago Style

Siraj, Shahneela, Meraj Raheem, Durr e Sameen Kamran, Afshan Mehboob Khan, Naila Parveen, and Masood Anwar Qureshi. "Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers." Rawal Medical Journal 45 (2020), 593-597.



MLA (The Modern Language Association) Style

Siraj, Shahneela, Meraj Raheem, Durr e Sameen Kamran, Afshan Mehboob Khan, Naila Parveen, and Masood Anwar Qureshi. "Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers." Rawal Medical Journal 45.3 (2020), 593-597. Print.



APA (American Psychological Association) Style

Siraj, S., Raheem, . M., Kamran, . D. e. S., Khan, . A. M., Parveen, . N. & Qureshi, . M. A. (2020) Serum insulin levels and anthropometric indices in macrosomic neonates; a comparative study between fetuses of diabetic and non-diabetic mothers. Rawal Medical Journal, 45 (3), 593-597.








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