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Original Research 
RMJ. 2019; 44(3): 509-512


Efficacy of corticosteroids in acute bronchiolitis: short term outcomes

Shaheen Ahmad, Sohail Shahzad, Umar Nawaz Khan, Muhammad Ahsan Shahzad, Mohid Ahmad, Maheen Ahmad.

Abstract
Objective: To determine short term efficacy of corticosteroids, when added to beta 2 agonist, in acute bronchiolitis.
Methodology: This randomized controlled trial was conducted at pediatric department in Combined Military Hospital, Abbottabad, Pakistan from January to June 2018. A sample size of 80 patients was calculated using WHO calculator. Non probability consecutive sampling was used. Patients were randomly divided into two groups; Group A was given oral prednisone for 3 days while group B placebo. All were followed after 7 days. SPSS version 24 was used for data analysis. Chi-square test was applied. P≤0.05 was considered significant.
Results: Out of 80 infants, there were 44 (55%) male and 36(45%) female. Mean age was 11.4±1.5 months. Corticosteroids showed significant reduction in respiratory rate (p=0.02), oxygen saturation SpO2(p=0.001), length of hospital stay (p<0.001) and wheezing (p<0.001) as short term outcome as compare to placebo.
Conclusion: Corticosteroids were effective treatment of choice in terms of short term outcome with limited complications, when used for 3 days in acute bronchiolitis.

Key words: Corticosteroids, acute brochiolitis, prednisone.


 
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How to Cite this Article
Pubmed Style

Ahmad S, Shahzad S, Khan UN, Shahzad MA, Ahmad M, Ahmad M. Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. RMJ. 2019; 44(3): 509-512.


Web Style

Ahmad S, Shahzad S, Khan UN, Shahzad MA, Ahmad M, Ahmad M. Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. http://www.rmj.org.pk/?mno=29649 [Access: October 23, 2019].


AMA (American Medical Association) Style

Ahmad S, Shahzad S, Khan UN, Shahzad MA, Ahmad M, Ahmad M. Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. RMJ. 2019; 44(3): 509-512.



Vancouver/ICMJE Style

Ahmad S, Shahzad S, Khan UN, Shahzad MA, Ahmad M, Ahmad M. Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. RMJ. (2019), [cited October 23, 2019]; 44(3): 509-512.



Harvard Style

Ahmad, S., Shahzad, . S., Khan, . U. N., Shahzad, . M. A., Ahmad, . M. & Ahmad, . M. (2019) Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. RMJ, 44 (3), 509-512.



Turabian Style

Ahmad, Shaheen, Sohail Shahzad, Umar Nawaz Khan, Muhammad Ahsan Shahzad, Mohid Ahmad, and Maheen Ahmad. 2019. Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. Rawal Medical Journal, 44 (3), 509-512.



Chicago Style

Ahmad, Shaheen, Sohail Shahzad, Umar Nawaz Khan, Muhammad Ahsan Shahzad, Mohid Ahmad, and Maheen Ahmad. "Efficacy of corticosteroids in acute bronchiolitis: short term outcomes." Rawal Medical Journal 44 (2019), 509-512.



MLA (The Modern Language Association) Style

Ahmad, Shaheen, Sohail Shahzad, Umar Nawaz Khan, Muhammad Ahsan Shahzad, Mohid Ahmad, and Maheen Ahmad. "Efficacy of corticosteroids in acute bronchiolitis: short term outcomes." Rawal Medical Journal 44.3 (2019), 509-512. Print.



APA (American Psychological Association) Style

Ahmad, S., Shahzad, . S., Khan, . U. N., Shahzad, . M. A., Ahmad, . M. & Ahmad, . M. (2019) Efficacy of corticosteroids in acute bronchiolitis: short term outcomes. Rawal Medical Journal, 44 (3), 509-512.








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