Open Access and Peer-reviewed
Home Journal Issues Guide for Authors Editorial Board Aims & Scope About Journal News & Announcements


Original Research 
RMJ. 2019; 44(2): 414-417


Serum Midkine levels in systemic lupus erythematosus

Blondina Marpaung, Andi Raga Ginting, OK Moehad Sjah.

Abstract
Objective: To compare serum level MK in SLE patients and control and to analyze the relation between the serum MK level and disease activity in SLE.
Methodology: This cross-sectional study was conducted in Adam Malik Hospital from January to June 2017. Diagnosis of SLE was established according to the Systemic Lupus International Collaborating Clinics (SLICC) classification criteria and disease activity was assessed using the Mexican Systemic lupus erythematosus disease activity index (MEX-SLEDAI). Data analysis was performed using SPSS version 22. p<0.05 was considered statistically significant.
Results: There were 90 subjects and divided into 2 groups: SLE patients group (n=40) and healthy control group (n=50). Midkine levels were increased in the serum of SLE patients compared by health control (p<0.001). Elevated Midkine serum levels was significant difference between active disease and remision (p=0.018).
Conclusion: Elevated Midkine serum level could be a marker of SLE disease activity and have a role in the pathogenesis of SLE.

Key words: Midkine, systemic lupus erythematosus, arthralgias.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Blondina Marpaung
Articles by Andi Raga Ginting
Articles by OK Moehad Sjah
on Google
on Google Scholar
Article Statistics
 Viewed: 1159
Downloaded: 77
Cited: 0


How to Cite this Article
Pubmed Style

Marpaung B, Ginting AR, Sjah OM. Serum Midkine levels in systemic lupus erythematosus. RMJ. 2019; 44(2): 414-417.


Web Style

Marpaung B, Ginting AR, Sjah OM. Serum Midkine levels in systemic lupus erythematosus. http://www.rmj.org.pk/?mno=288776 [Access: June 18, 2019].


AMA (American Medical Association) Style

Marpaung B, Ginting AR, Sjah OM. Serum Midkine levels in systemic lupus erythematosus. RMJ. 2019; 44(2): 414-417.



Vancouver/ICMJE Style

Marpaung B, Ginting AR, Sjah OM. Serum Midkine levels in systemic lupus erythematosus. RMJ. (2019), [cited June 18, 2019]; 44(2): 414-417.



Harvard Style

Marpaung, B., Ginting, . A. R. & Sjah, . O. M. (2019) Serum Midkine levels in systemic lupus erythematosus. RMJ, 44 (2), 414-417.



Turabian Style

Marpaung, Blondina, Andi Raga Ginting, and OK Moehad Sjah. 2019. Serum Midkine levels in systemic lupus erythematosus. Rawal Medical Journal, 44 (2), 414-417.



Chicago Style

Marpaung, Blondina, Andi Raga Ginting, and OK Moehad Sjah. "Serum Midkine levels in systemic lupus erythematosus." Rawal Medical Journal 44 (2019), 414-417.



MLA (The Modern Language Association) Style

Marpaung, Blondina, Andi Raga Ginting, and OK Moehad Sjah. "Serum Midkine levels in systemic lupus erythematosus." Rawal Medical Journal 44.2 (2019), 414-417. Print.



APA (American Psychological Association) Style

Marpaung, B., Ginting, . A. R. & Sjah, . O. M. (2019) Serum Midkine levels in systemic lupus erythematosus. Rawal Medical Journal, 44 (2), 414-417.








AUTHOR LOGIN

REVIEWER LOGIN

Indexed
&
Abstracted


Indexed in WHO Index Medicus IMEMR, Emromedex, Pakmedinet, ExtraMED and Scopus

  Approved by the Higher Education Commission of Pakistan and Pakistan Medical and Dental Council


ABOUT JOURNAL
POLICIES
STATEMENTS

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.

The articles in Rawal Medical Journal are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.