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Original Research Open Access
RMJ. 2017; 42(3): 385-389


Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation

Sana Sarfaraz, Rahila Najam.

Abstract
Objective: Beta vulgaris is an important part of daily diet and is consumed in salads. Current study was conducted to investigate the anti-inflammatory potential of lyophilized beet root powder.
Methodology: Albino rats weighing 140-200gm were chosen for this study. They were divided into six equal groups. For ethanoic acid induced paw edema model, group I was labeled as control and was orally given 1ml distilled water; groups II was given Ibuprofen as standard (400mg/70kg) and group III was given aqueous solution of lyophilized Beta vulgaris at dose of 500mg/kg. 30 minutes after giving these treatments 0.1 ml of 1% w/v ethanoic acid was administered in the subplantar tissue of rat paw. For carrrageenan induced paw edema method, group I (a), group II (a) and group III (a) were given same treatment as above divided groups; only difference was that they were administered 0.1ml of 1% carrageenan in subplantar tissue of rat paw after oral treatment. Swelling of paw was measured using Plethysmometer.
Results: Beta vulgaris had highly significant anti-inflammatory activity (p<0.001). In ethanoic acid paw edema method, the highest percentage inhibition was 26.9% and it was observed 2 hours after administration of ethanoic acid. In carrageenan induced paw edema, Beta vulgaris showed highest inhibitory percentage (41.4%), which was seen after 2 hours of administration of carrageenan.
Conclusion: Beta vulgaris had significant anti-inflammatory effects that may be of potential benefit in different inflammatory conditions. The anti-inflammatory effect is observed due to presence of betalain.

Key words: Beta vulgaris, carrageenan, ethanoic acid, inflammation.


 
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How to Cite this Article
Pubmed Style

Sarfaraz S, Najam R. Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. RMJ. 2017; 42(3): 385-389.


Web Style

Sarfaraz S, Najam R. Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. http://www.rmj.org.pk/?mno=257940 [Access: December 17, 2017].


AMA (American Medical Association) Style

Sarfaraz S, Najam R. Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. RMJ. 2017; 42(3): 385-389.



Vancouver/ICMJE Style

Sarfaraz S, Najam R. Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. RMJ. (2017), [cited December 17, 2017]; 42(3): 385-389.



Harvard Style

Sarfaraz, S. & Najam, R. (2017) Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. RMJ, 42 (3), 385-389.



Turabian Style

Sarfaraz, Sana, and Rahila Najam. 2017. Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. Rawal Medical Journal, 42 (3), 385-389.



Chicago Style

Sarfaraz, Sana, and Rahila Najam. "Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation." Rawal Medical Journal 42 (2017), 385-389.



MLA (The Modern Language Association) Style

Sarfaraz, Sana, and Rahila Najam. "Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation." Rawal Medical Journal 42.3 (2017), 385-389. Print.



APA (American Psychological Association) Style

Sarfaraz, S. & Najam, R. (2017) Evaluation of anti-inflammatory effect of natural dietary supplement Beta vulgaris (Beet root) in animal models of inflammation. Rawal Medical Journal, 42 (3), 385-389.




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