Histopathological pattern of prostate lesions in patients suffering from prostatism

Mohammad Sajjad Khattak, Zardali Khan, Mohammad Akram

Abstract
Objective: To study the histopathological pattern of prostatic lesions in patients suffering from prostatism.
Methodology: This retrospective descriptive study was conducted in Pathology Department Bannu Medical College, Bannu, Khyber Pakhthunkhwa, Pakistan and included 157 prostate biopsies in form of open Trans Vesical Prostatectomy (TVP), Trans Urethral Resections of Prostate (TURP) and needle biopsies performed from January 2013 to December 2015. All biopsy slides were processed for H&E staining and mounted. A minimum of four and maximum of ten sections were taken from each specimen. Insufficient autolysed specimen and those biopsies where immunohistochemistry was required were excluded from the study.
Results: A total of 157 prostatic biopsy specimens were received in pathology laboratory with mean age of 58.68±12.71 years (range 40 to 85 years). Amongst these, benign lesions were 142 (90.44%), malignant tumors were 15 (9.56%). Benign to malignant ratio was 9.46:1.
Conclusion: Benign prostatic hyperplasia alone and in combination with chronic prostatitis was the commonest non neoplastic lesions followed by neoplastic lesion of adenocarcinoma.

Key words: Prostate gland, benign prostatic hyperplasia, prostate adenocarcinoma.

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