Open Access and Peer-reviewed
Home Journal Issues Guide for Authors Editorial Board Aims & Scope About Journal News & Announcements


Original Research 


Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan

Altaf Ahmed Shaikh, Anum Shaikh, Amber Tahir.

Abstract
Objective: To study the pattern of antimicrobial sensitivity to Salmonella Typhoid in Southern part of Pakistan.
Methodology: This retrospective analysis included all blood culture samples positive for Salmonella typhi, paratyphi A, and paratyphi B in adults of age >18 years seen at Ghulam Muhammad Mahar Medical College and Hospital, Sukkur from January to December 2017. Multidrug resistant (MDR) typhoid was defined as the strains resistant to all first line agents. Extended drug resistant (XDR) cases were taken as those resistant to all first line agents along with resistance to fluoroquinolones and ceftriaxone. Data were analyzed using SPSS version. 21.0
Results: Of 465 salmonella positive isolates, 69.4% were S. typhi, 20.6% were S. paratyphi A and 9.9% were S. paratyphi B. S. typhi was more common in males (52.6%). Among the S. typhi strains, ciprofloxacin showed highest resistance (62.5%); ceftriaxone showed a resistance of 20.7%. There were 17% MDR and 3.7% XDR strains of S. typhi.
Conclusion: There is alarming rise in antimicrobial resistance against Salmonellae in Pakistan. Surveillance studies must be used to monitor the typhoid spread and its evolving antimicrobial resistance.

Key words: Antibiotic resistance, typhoid, enteric fever, salmonella, Pakistan.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Altaf Ahmed Shaikh
Articles by Anum Shaikh
Articles by Amber Tahir
on Google
on Google Scholar
Article Statistics
 Viewed: 603
Downloaded: 103
Cited: 0


How to Cite this Article
Pubmed Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ. 2019; 44(1): 7-10.


Web Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. http://www.rmj.org.pk/?mno=22011 [Access: March 22, 2019].


AMA (American Medical Association) Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ. 2019; 44(1): 7-10.



Vancouver/ICMJE Style

Shaikh AA, Shaikh A, Tahir A. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ. (2019), [cited March 22, 2019]; 44(1): 7-10.



Harvard Style

Shaikh, A. A., Shaikh, . A. & Tahir, . A. (2019) Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. RMJ, 44 (1), 7-10.



Turabian Style

Shaikh, Altaf Ahmed, Anum Shaikh, and Amber Tahir. 2019. Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. Rawal Medical Journal, 44 (1), 7-10.



Chicago Style

Shaikh, Altaf Ahmed, Anum Shaikh, and Amber Tahir. "Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan." Rawal Medical Journal 44 (2019), 7-10.



MLA (The Modern Language Association) Style

Shaikh, Altaf Ahmed, Anum Shaikh, and Amber Tahir. "Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan." Rawal Medical Journal 44.1 (2019), 7-10. Print.



APA (American Psychological Association) Style

Shaikh, A. A., Shaikh, . A. & Tahir, . A. (2019) Antimicrobial resistance trends of Typhoidal Salmonellae In Southern Pakistan. Rawal Medical Journal, 44 (1), 7-10.








AUTHOR LOGIN

REVIEWER LOGIN

Indexed
&
Abstracted


Indexed in WHO Index Medicus IMEMR, Emromedex, Pakmedinet, ExtraMED and Scopus

  Approved by the Higher Education Commission of Pakistan and Pakistan Medical and Dental Council


ABOUT JOURNAL
POLICIES
STATEMENTS

This is an open access journal which means that all content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the Budapest Open Access Initiative (BOAI) definition of open access.

The articles in Rawal Medical Journal are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.