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Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures

Masroor Ahmed, Ghulam Hussain, Mukesh Kumar, Rukhsana Hamid, Nida.

Abstract
Objective: To evaluate the efficacy of tranexamic acid in reducing blood loss in patient undergoing dynamic hip screw (DHS) surgery for intertrochanteric fracture.
Methodology: In this randomized control trial, 120 patients undergoing DHS surgery between July 2015 to July 2017 were randomly divided into two groups (60 cases in each group); group A (intervention group: received 15mg/kg tranexamic acid), whereas group B (control group: given same dose of physiological saline). The age, weight, duration of fracture, height, pre-op and post-op hemoglobin and HCT and estimated blood loss were recorded and compared in two groups.
Results: Preoperative and post hematocrit values were significantly different in two groups (p value 0.01 and 0.001, respectively). The mean estimated blood loss was 395.78204 in group A and 427.8146.9 in group B (p=0.001).
Conclusion: Treatment with Tranexamic acid had decreased the blood loss during intertrochanteric hip fracture surgery.

Key words: Intertrochanteric, hip, dynamic hip screw (DHS); Blood loss, fracture, Tranexamic acid, randomized control trial (RCT)


 
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How to Cite this Article
Pubmed Style

Ahmed M, Hussain G, Kumar M, Hamid R, Nida . Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. RMJ. 2019; 44(1): 79-82.


Web Style

Ahmed M, Hussain G, Kumar M, Hamid R, Nida . Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. http://www.rmj.org.pk/?mno=20343 [Access: July 18, 2019].


AMA (American Medical Association) Style

Ahmed M, Hussain G, Kumar M, Hamid R, Nida . Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. RMJ. 2019; 44(1): 79-82.



Vancouver/ICMJE Style

Ahmed M, Hussain G, Kumar M, Hamid R, Nida . Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. RMJ. (2019), [cited July 18, 2019]; 44(1): 79-82.



Harvard Style

Ahmed, M., Hussain, . G., Kumar, . M., Hamid, . R. & Nida, . (2019) Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. RMJ, 44 (1), 79-82.



Turabian Style

Ahmed, Masroor, Ghulam Hussain, Mukesh Kumar, Rukhsana Hamid, and Nida. 2019. Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. Rawal Medical Journal, 44 (1), 79-82.



Chicago Style

Ahmed, Masroor, Ghulam Hussain, Mukesh Kumar, Rukhsana Hamid, and Nida. "Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures." Rawal Medical Journal 44 (2019), 79-82.



MLA (The Modern Language Association) Style

Ahmed, Masroor, Ghulam Hussain, Mukesh Kumar, Rukhsana Hamid, and Nida. "Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures." Rawal Medical Journal 44.1 (2019), 79-82. Print.



APA (American Psychological Association) Style

Ahmed, M., Hussain, . G., Kumar, . M., Hamid, . R. & Nida, . (2019) Reduction in blood loss with tranexamic acid in dynamic hip screw surgery for intertrochanteric hip fractures. Rawal Medical Journal, 44 (1), 79-82.








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