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Original Research 
RMJ. 2015; 40(2): 191-196


Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang.

Abstract
Objective: Emergence agitation (EA) is defined as a transient condition in which emergence from general anesthesia is accompanied by psychomotor agitation. Dexmedetomidine (Dex) is known to reduce EA in children. The objective of this study was to determine the effects of intraoperative Dex on EA undergoing closed reduction of a nasal bone fracture.
Methodology: Thirty-eight male patients, ages 18 to 60 years, were randomized to receive a single intraoperative dose of Dex 1.0 µg/kg (Group D) or the same volume as normal saline (Group N) over 5 minutes before endotracheal intubation. The Richmond agitation sedation scale (RASS) was utilized to assess the intensity of the EA.
Results: EA was observed in 12 patients in group D compared with 18 patients in group N (P=0.042). Heart rate was significantly lower one minute after intubation (P=0.032), one minute before extubation (P=0.023), and upon arrival in the PACU (P=0.013). The mean blood pressure was lower one minute after extubation (P=0.004). Postoperative pain was significantly less in group D (P=0.050).
Conclusion: A single intraoperative dose of Dex was an effective method to reduce EA in adult patients undergoing closed reduction for a nasal bone fracture.

Key words: Dexmedetomidine, emergence agitation, general anesthesia, nasal bone fracture, Richmond agitation sedation scale


 
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How to Cite this Article
Pubmed Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. RMJ. 2015; 40(2): 191-196.

Web Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. https://www.rmj.org.pk/?mno=178494 [Access: December 07, 2023].

AMA (American Medical Association) Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. RMJ. 2015; 40(2): 191-196.


Vancouver/ICMJE Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. RMJ. (2015), [cited December 07, 2023]; 40(2): 191-196.


Harvard Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang (2015) Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. RMJ, 40 (2), 191-196.


Turabian Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. 2015. Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. Rawal Medical Journal, 40 (2), 191-196.


Chicago Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. "Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture." Rawal Medical Journal 40 (2015), 191-196.


MLA (The Modern Language Association) Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang. "Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture." Rawal Medical Journal 40.2 (2015), 191-196. Print.


APA (American Psychological Association) Style

Jae-Wook Jung, Yong Han Kim, Ki Hwa Lee, Byeong-Cheol Lee, Hey Ran Choi, Kyung Woo Kim, Si Ra Bang (2015) Effect of dexmedetomidine on emergence agitation in male patients undergoing closed reduction of a nasal bone fracture. Rawal Medical Journal, 40 (2), 191-196.


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