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Original Research 
RMJ. 2015; 40(2): 207-209


Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel.

Abstract
Objective: This study aimed at analyzing the association between recurrent spontaneous abortion and prothrombin G20210 gene mutation in Sudanese women.
Methodology: This prospective analytical case control study was carried out at Omdurman Maternity Hospital, Sudan and included 100 Sudanese women who experienced three or more of the adverse pregnancy outcomes during their reproductive age. 96 controls were also included. Cases and controls were tested for the above mutations.
Results: Out of 100 case, 3 (3%) had gene mutation and none was found control group (P =0.091).
Conclusion: We found limited importance of prothrombin mutation as genetic risk factor among women with recurrent spontaneous abortion. There was no significant association between cases carriage any of this mutation and risk with recurrent pregnancy miscarriage.

Key words: Factor prothrombin, mutation, Sudanese pregnant women, recurrent miscarriage


 
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How to Cite this Article
Pubmed Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. RMJ. 2015; 40(2): 207-209.

Web Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. https://www.rmj.org.pk/?mno=174703 [Access: December 05, 2023].

AMA (American Medical Association) Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. RMJ. 2015; 40(2): 207-209.


Vancouver/ICMJE Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. RMJ. (2015), [cited December 05, 2023]; 40(2): 207-209.


Harvard Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel (2015) Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. RMJ, 40 (2), 207-209.


Turabian Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. 2015. Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. Rawal Medical Journal, 40 (2), 207-209.


Chicago Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. "Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions." Rawal Medical Journal 40 (2015), 207-209.


MLA (The Modern Language Association) Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel. "Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions." Rawal Medical Journal 40.2 (2015), 207-209. Print.


APA (American Psychological Association) Style

Asaad Mohammed Ahmed Abd Allah Babker, Fath Elrahman Mahdi Hassan Gameel (2015) Molecular characterization of Prothrombin G20210A gene mutations in pregnant Sudanese women with spontaneous recurrent abortions. Rawal Medical Journal, 40 (2), 207-209.


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