ISSN 0303-5212
 

Original Research 
RMJ. 2014; 39(4): 376-380


Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta.

Abstract
Objectives: To determine the incidence of osteopenia and osteoporosis in women aged between 40-65 years and find the association between BMD and biochemical parameters.
Methods: The present study was conducted in women aged between 40-65 years visiting Gynaecology Outpatient Department. Body mass index (BMI) was calculated, BMD values were measured in terms of T-scores and Z-scores. Estimation of serum biochemical and serum FSH level was done.
The statistical analysis was done using SPSS (Statistical Package for Social Sciences) Version 15.0.
Result: Low BMD was observed in 35% out of which 30% had oesteopenia and 5% were having osteoporosis. 88.6% of subjects having BMI between 18 to 25 kg/m2 had low BMD, whereas only 11.4% having BMI between 24-30 kg/m2 were found to be suffering from low bone mass. Low serum calcium levels were seen in 54.3% women having low BMD. Higher levels of serum alkaline phosphatase and serum FSH seemed to be associated with low BMD.
Conclusions: We found that 65.7% of subjects between 40-50 years and 22.9% of cases between 51 to 60 years had low BMD. In women having serum calcium level less than 8.7 mg% chance of having osteopenia and osteoprosis was almost similar in both perimenopausal and post menopausal women. Higher FSH levels were found to be associated with bone loss.

Key words: Osteoporosis, bone mineral density, biochemical markers


 
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Pubmed Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. RMJ. 2014; 39(4): 376-380.


Web Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. https://www.rmj.org.pk/?mno=159849 [Access: December 05, 2023].


AMA (American Medical Association) Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. RMJ. 2014; 39(4): 376-380.



Vancouver/ICMJE Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. RMJ. (2014), [cited December 05, 2023]; 39(4): 376-380.



Harvard Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta (2014) Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. RMJ, 39 (4), 376-380.



Turabian Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. 2014. Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. Rawal Medical Journal, 39 (4), 376-380.



Chicago Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. "Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women." Rawal Medical Journal 39 (2014), 376-380.



MLA (The Modern Language Association) Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta. "Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women." Rawal Medical Journal 39.4 (2014), 376-380. Print.



APA (American Psychological Association) Style

Uma Gupta, Shruti Sharma, Narendra Kumar Gupta (2014) Bone mineral density (BMD) and biochemical markers in evaluation of bone health in women. Rawal Medical Journal, 39 (4), 376-380.